Net absorption of fluid in uninfected and ETEC-infected piglet small intestine: effect of osmolality

J.L. Kiers, M.R.J. Nout, F.M. Rombouts, M.J.A. Nabuurs, J. van der Meulen

Research output: Chapter in Book/Report/Conference proceedingAbstract

Abstract

After (early) weaning, piglets frequently have diarrhoea associated with enterotoxic
Escherichia coli (ETEC) and rotavirus. Using the small intestine segment perfusion model
with uninfected and ETEC-infected segments, we have investigated the effect of osmolality on net fluid absorption in piglets. Increased osmolality resulted in a decreased net
fluid absorption. Regression analysis showed a linear relationship between osmolality
and net fluid absorption both for uninfected and ETEC-infected segments. ETEC infection
resulted in a decrease in net fluid absorption independent of the osmolality. Although
hypotonic solutions do not eliminate the decreased net fluid absorption observed in ETEC
infection, it is shown that low osmolality may promote net fluid absorption in piglets
with diarrhoea.
Original languageEnglish
Title of host publicationDigestive physiology of pigs : 8th Symposium on Digestive Physiology in Pigs, Uppsala, Sweden, 2000
EditorsJ.E. Lindberg, B. Ogle
Place of PublicationWallingford
PublisherCABI
Chapter76
Pages277-279
ISBN (Print)9780851995175
DOIs
Publication statusPublished - 2001
Event8th Symposium on Digestive Physiology in Pigs - Uppsala
Duration: 20 Jun 200022 Jun 2000

Conference

Conference8th Symposium on Digestive Physiology in Pigs
CityUppsala
Period20/06/0022/06/00

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