Natural variation at Strubbelig Receptor Kinase 3 drives immune-triggered incompatibilities between Arabidopsis thaliana accessions

R. Alcazar, A.V. Garcia, I. Kronholm, J. De Meaux, M. Koornneef, J.E. Parker, M. Reymond

Research output: Contribution to journalArticleAcademicpeer-review

77 Citations (Scopus)

Abstract

Accumulation of genetic incompatibilities within species can lead to reproductive isolation and, potentially, speciation. In this study, we show that allelic variation at SRF3 (Strubbelig Receptor Family 3), encoding a receptor-like kinase, conditions the occurrence of incompatibility between Arabidopsis thaliana accessions. The geographical distribution of SRF3 alleles reveals that allelic forms causing epistatic incompatibility with a Landsberg erecta allele at the RPP1 resistance locus are present in A. thaliana accessions in central Asia. Incompatible SRF3 alleles condition for an enhanced early immune response to pathogens as compared to the resistance-dampening effect of compatible SRF3 forms in isogenic backgrounds. Variation in disease susceptibility suggests a basis for the molecular patterns of a recent selective sweep detected at the SRF3 locus in central Asian populations
Original languageEnglish
Pages (from-to)1135-1139
JournalNature Genetics
Volume42
DOIs
Publication statusPublished - 2010

Keywords

  • systemic acquired-resistance
  • mpk4 activation
  • plants
  • eds1
  • responses
  • selection
  • proteins
  • mekk1
  • pad4

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