With sodium citrate added to the basal ration there was a positive correlation between amount of sodium and rate of resumed growth. Optimum growth was achieved with 0. 1 - 0.2 % added Na. Na could not be replaced by K or Li. K did not possess the Na-expelling effect postulated by Bunge because Na requirement was independent of K in feed and because a fixed addition of Na gave a reproducible growth in depleted rats, however much K in diet. N excretion during deficiency mainly as urea, was excessive, and it seemed that Na was needed for protein synthesis. Conception was normal but reproduction was impossible. Weight gain during pregnancy was much reduced and no milk was secreted. After severe Na deficiency kidneys could not conserve sodium until an ample supply had been available for a short while. Body temperature was normal during deficiency but was rather high some time after resupplying sodium.
|Qualification||Doctor of Philosophy|
|Award date||13 Jul 1934|
|Place of Publication||Deventer|
|Publication status||Published - 1934|
- body composition
- chemical analysis
- environmental degradation