Nanoparticle tracking analysis of gold nanoparticles in aqueous media through an inter-laboratory comparison

Sophie M. Briffa; Jo Sullivan; Agnieszka Siupa; Pauline Carnell-Morris; Michele Carboni; Kerstin Jurkschat; Ruud J.B. Peters; Carolin Schultz; Kang Hee Seol; Sook Jin Kwon; Sehee Park; Tae Hyun Yoon; Colin Johnston; Stephen Lofts; Eugenia Valsami-Jones

doi:10.3791/61741

Nanoparticle tracking analysis of gold nanoparticles in aqueous media through an inter-laboratory comparison

Sophie M. Briffa, Jo Sullivan, Agnieszka Siupa, Pauline Carnell-Morris, Michele Carboni, Kerstin Jurkschat, Ruud J.B. Peters, Carolin Schultz, Kang Hee Seol, Sook Jin Kwon, Sehee Park, Tae Hyun Yoon, Colin Johnston, Stephen Lofts, Eugenia Valsami-Jones

Team Organic Contaminants

Research output: Contribution to journal › Article › Academic › peer-review

Abstract

In the field of nanotechnology, analytical characterization plays a vital role in understanding the behavior and toxicity of nanomaterials (NMs). Characterization needs to be thorough and the technique chosen should be well-suited to the property to be determined, the material being analyzed and the medium in which it is present. Furthermore, the instrument operation and methodology need to be well-developed and clearly understood by the user to avoid data collection errors. Any discrepancies in the applied method or procedure can lead to differences and poor reproducibility of obtained data. This paper aims to clarify the method to measure the hydrodynamic diameter of gold nanoparticles by means of Nanoparticle Tracking Analysis (NTA). This study was carried out as an inter-laboratory comparison (ILC) amongst seven different laboratories to validate the standard operating procedure’s performance and reproducibility. The results obtained from this ILC study reveal the importance and benefits of detailed standard operating procedures (SOPs), best practice updates, user knowledge, and measurement automation.

Original language	English
Article number	e61741
Number of pages	12
Journal	Journal of Visualized Experiments
Volume	2020
Issue number	164
DOIs	https://doi.org/10.3791/61741
Publication status	Published - Oct 2020

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1 Active

Risico's nanotechnologie biobeschikbaarheid en toxicologie contrafinanciering (KB-37-002-001, KB-23-002-005, KB-15-003-010)
Peters, R.
1/01/11 → 31/12/21
Project: EZproject

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Briffa, S. M., Sullivan, J., Siupa, A., Carnell-Morris, P., Carboni, M., Jurkschat, K., Peters, R. J. B., Schultz, C., Seol, K. H., Kwon, S. J., Park, S., Yoon, T. H., Johnston, C., Lofts, S., & Valsami-Jones, E. (2020). Nanoparticle tracking analysis of gold nanoparticles in aqueous media through an inter-laboratory comparison. Journal of Visualized Experiments, 2020(164), [e61741]. https://doi.org/10.3791/61741

Briffa, Sophie M. ; Sullivan, Jo ; Siupa, Agnieszka ; Carnell-Morris, Pauline ; Carboni, Michele ; Jurkschat, Kerstin ; Peters, Ruud J.B. ; Schultz, Carolin ; Seol, Kang Hee ; Kwon, Sook Jin ; Park, Sehee ; Yoon, Tae Hyun ; Johnston, Colin ; Lofts, Stephen ; Valsami-Jones, Eugenia. / Nanoparticle tracking analysis of gold nanoparticles in aqueous media through an inter-laboratory comparison. In: Journal of Visualized Experiments. 2020 ; Vol. 2020, No. 164.

@article{328bca762aa04a24a1c479c04bff039a,

title = "Nanoparticle tracking analysis of gold nanoparticles in aqueous media through an inter-laboratory comparison",

abstract = "In the field of nanotechnology, analytical characterization plays a vital role in understanding the behavior and toxicity of nanomaterials (NMs). Characterization needs to be thorough and the technique chosen should be well-suited to the property to be determined, the material being analyzed and the medium in which it is present. Furthermore, the instrument operation and methodology need to be well-developed and clearly understood by the user to avoid data collection errors. Any discrepancies in the applied method or procedure can lead to differences and poor reproducibility of obtained data. This paper aims to clarify the method to measure the hydrodynamic diameter of gold nanoparticles by means of Nanoparticle Tracking Analysis (NTA). This study was carried out as an inter-laboratory comparison (ILC) amongst seven different laboratories to validate the standard operating procedure{\textquoteright}s performance and reproducibility. The results obtained from this ILC study reveal the importance and benefits of detailed standard operating procedures (SOPs), best practice updates, user knowledge, and measurement automation.",

author = "Briffa, {Sophie M.} and Jo Sullivan and Agnieszka Siupa and Pauline Carnell-Morris and Michele Carboni and Kerstin Jurkschat and Peters, {Ruud J.B.} and Carolin Schultz and Seol, {Kang Hee} and Kwon, {Sook Jin} and Sehee Park and Yoon, {Tae Hyun} and Colin Johnston and Stephen Lofts and Eugenia Valsami-Jones",

year = "2020",

month = oct,

doi = "10.3791/61741",

language = "English",

volume = "2020",

journal = "Journal of Visualized Experiments",

issn = "1940-087X",

publisher = "Journal of Visualized Experiments",

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Briffa, SM, Sullivan, J, Siupa, A, Carnell-Morris, P, Carboni, M, Jurkschat, K, Peters, RJB, Schultz, C, Seol, KH, Kwon, SJ, Park, S, Yoon, TH, Johnston, C, Lofts, S & Valsami-Jones, E 2020, 'Nanoparticle tracking analysis of gold nanoparticles in aqueous media through an inter-laboratory comparison', Journal of Visualized Experiments, vol. 2020, no. 164, e61741. https://doi.org/10.3791/61741

Nanoparticle tracking analysis of gold nanoparticles in aqueous media through an inter-laboratory comparison. / Briffa, Sophie M.; Sullivan, Jo; Siupa, Agnieszka; Carnell-Morris, Pauline; Carboni, Michele; Jurkschat, Kerstin; Peters, Ruud J.B.; Schultz, Carolin; Seol, Kang Hee; Kwon, Sook Jin; Park, Sehee; Yoon, Tae Hyun; Johnston, Colin; Lofts, Stephen; Valsami-Jones, Eugenia.

In: Journal of Visualized Experiments, Vol. 2020, No. 164, e61741, 10.2020.

Research output: Contribution to journal › Article › Academic › peer-review

TY - JOUR

T1 - Nanoparticle tracking analysis of gold nanoparticles in aqueous media through an inter-laboratory comparison

AU - Briffa, Sophie M.

AU - Sullivan, Jo

AU - Siupa, Agnieszka

AU - Carnell-Morris, Pauline

AU - Carboni, Michele

AU - Jurkschat, Kerstin

AU - Peters, Ruud J.B.

AU - Schultz, Carolin

AU - Seol, Kang Hee

AU - Kwon, Sook Jin

AU - Park, Sehee

AU - Yoon, Tae Hyun

AU - Johnston, Colin

AU - Lofts, Stephen

AU - Valsami-Jones, Eugenia

PY - 2020/10

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AB - In the field of nanotechnology, analytical characterization plays a vital role in understanding the behavior and toxicity of nanomaterials (NMs). Characterization needs to be thorough and the technique chosen should be well-suited to the property to be determined, the material being analyzed and the medium in which it is present. Furthermore, the instrument operation and methodology need to be well-developed and clearly understood by the user to avoid data collection errors. Any discrepancies in the applied method or procedure can lead to differences and poor reproducibility of obtained data. This paper aims to clarify the method to measure the hydrodynamic diameter of gold nanoparticles by means of Nanoparticle Tracking Analysis (NTA). This study was carried out as an inter-laboratory comparison (ILC) amongst seven different laboratories to validate the standard operating procedure’s performance and reproducibility. The results obtained from this ILC study reveal the importance and benefits of detailed standard operating procedures (SOPs), best practice updates, user knowledge, and measurement automation.

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DO - 10.3791/61741

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VL - 2020

JO - Journal of Visualized Experiments

JF - Journal of Visualized Experiments

SN - 1940-087X

IS - 164

M1 - e61741

ER -

Nanoparticle tracking analysis of gold nanoparticles in aqueous media through an inter-laboratory comparison

Abstract

Access to Document

Risico's nanotechnologie biobeschikbaarheid en toxicologie contrafinanciering (KB-37-002-001, KB-23-002-005, KB-15-003-010)

Cite this