Multiplex nucleic acid detection

C.D. Schoen; M. Szemes; P.J.M. Bonants

Multiplex nucleic acid detection

C.D. Schoen (Inventor), M. Szemes (Inventor), P.J.M. Bonants (Inventor)

Research output: Patent

Abstract

The present invention relates to a novel multiplex detection of nucleic acid targets in a sample. This is accomplished by using novel padlock probes which contain a unique cleavage site for linearization and a first member of a binding pair for isolation of the padlock probe from the sample. Three different designs of the padlock probes are described and examples are shown for ligation, amplification and qualitative and quantitative detection. The combination of these features gives a fast, accurate and specific multiplex detection assay

Original language	English
Patent number	WO2007061284
Priority date	22/11/05
Publication status	Published - 31 May 2007

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title = "Multiplex nucleic acid detection",

abstract = "The present invention relates to a novel multiplex detection of nucleic acid targets in a sample. This is accomplished by using novel padlock probes which contain a unique cleavage site for linearization and a first member of a binding pair for isolation of the padlock probe from the sample. Three different designs of the padlock probes are described and examples are shown for ligation, amplification and qualitative and quantitative detection. The combination of these features gives a fast, accurate and specific multiplex detection assay",

author = "C.D. Schoen and M. Szemes and P.J.M. Bonants",

note = "International publication number: WO 2007/061284 (31.05.2007 Gazette 2007/22); WO2007061284",

year = "2007",

month = may,

day = "31",

language = "English",

type = "Patent",

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TY - PAT

T1 - Multiplex nucleic acid detection

AU - Schoen, C.D.

AU - Szemes, M.

AU - Bonants, P.J.M.

N1 - International publication number: WO 2007/061284 (31.05.2007 Gazette 2007/22)

PY - 2007/5/31

Y1 - 2007/5/31

N2 - The present invention relates to a novel multiplex detection of nucleic acid targets in a sample. This is accomplished by using novel padlock probes which contain a unique cleavage site for linearization and a first member of a binding pair for isolation of the padlock probe from the sample. Three different designs of the padlock probes are described and examples are shown for ligation, amplification and qualitative and quantitative detection. The combination of these features gives a fast, accurate and specific multiplex detection assay

AB - The present invention relates to a novel multiplex detection of nucleic acid targets in a sample. This is accomplished by using novel padlock probes which contain a unique cleavage site for linearization and a first member of a binding pair for isolation of the padlock probe from the sample. Three different designs of the padlock probes are described and examples are shown for ligation, amplification and qualitative and quantitative detection. The combination of these features gives a fast, accurate and specific multiplex detection assay

M3 - Patent

M1 - WO2007061284

ER -

Multiplex nucleic acid detection

Abstract

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