Multi-block copolymers

F.A. de Wolf (Inventor), M.A. Cohen Stuart (Inventor), G. Eggink (Inventor), M.W.T. Werten (Inventor), A.A. Martens (Inventor)

Research output: PatentOther research output

Abstract

A multi-block copolymer comprises at least one hydrophilic collagen-like block and at least one silk-like block. The silk-like block comprises an amino acid sequence ((GA) m GX) n , wherein G is glycine, A is alanine, m and n are at least 2. X is an ionizable amino acid. The ionizable amino acid is inducible to bear a positive charge or a negative charge. The ionizable amino acid bearing the positive charge is preferably histidine and the one bearing the negative charge is preferably glutamic acid.
Original languageEnglish
Patent numberWO2009031095
Priority date7/09/07
Publication statusPublished - 23 Jun 2010

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Block copolymers
Bearings (structural)
Amino Acids
Silk
Histidine
Alanine
Glycine
Glutamic Acid
Collagen

Cite this

de Wolf, F. A., Cohen Stuart, M. A., Eggink, G., Werten, M. W. T., & Martens, A. A. (2010). Multi-block copolymers. (Patent No. WO2009031095).
de Wolf, F.A. (Inventor) ; Cohen Stuart, M.A. (Inventor) ; Eggink, G. (Inventor) ; Werten, M.W.T. (Inventor) ; Martens, A.A. (Inventor). / Multi-block copolymers. Patent No.: WO2009031095.
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abstract = "A multi-block copolymer comprises at least one hydrophilic collagen-like block and at least one silk-like block. The silk-like block comprises an amino acid sequence ((GA) m GX) n , wherein G is glycine, A is alanine, m and n are at least 2. X is an ionizable amino acid. The ionizable amino acid is inducible to bear a positive charge or a negative charge. The ionizable amino acid bearing the positive charge is preferably histidine and the one bearing the negative charge is preferably glutamic acid.",
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de Wolf, FA, Cohen Stuart, MA, Eggink, G, Werten, MWT & Martens, AA 2010, Multi-block copolymers, Patent No. WO2009031095.

Multi-block copolymers. / de Wolf, F.A. (Inventor); Cohen Stuart, M.A. (Inventor); Eggink, G. (Inventor); Werten, M.W.T. (Inventor); Martens, A.A. (Inventor).

Patent No.: WO2009031095.

Research output: PatentOther research output

TY - PAT

T1 - Multi-block copolymers

AU - de Wolf, F.A.

AU - Cohen Stuart, M.A.

AU - Eggink, G.

AU - Werten, M.W.T.

AU - Martens, A.A.

PY - 2010/6/23

Y1 - 2010/6/23

N2 - A multi-block copolymer comprises at least one hydrophilic collagen-like block and at least one silk-like block. The silk-like block comprises an amino acid sequence ((GA) m GX) n , wherein G is glycine, A is alanine, m and n are at least 2. X is an ionizable amino acid. The ionizable amino acid is inducible to bear a positive charge or a negative charge. The ionizable amino acid bearing the positive charge is preferably histidine and the one bearing the negative charge is preferably glutamic acid.

AB - A multi-block copolymer comprises at least one hydrophilic collagen-like block and at least one silk-like block. The silk-like block comprises an amino acid sequence ((GA) m GX) n , wherein G is glycine, A is alanine, m and n are at least 2. X is an ionizable amino acid. The ionizable amino acid is inducible to bear a positive charge or a negative charge. The ionizable amino acid bearing the positive charge is preferably histidine and the one bearing the negative charge is preferably glutamic acid.

M3 - Patent

M1 - WO2009031095

ER -

de Wolf FA, Cohen Stuart MA, Eggink G, Werten MWT, Martens AA, inventors. Multi-block copolymers. WO2009031095. 2010 Jun 23.