Microcontact Printing onto Oxide-Free Silicon via Highly Reactive Acid Fluoride-Functionalized Monolayers

L.M.W. Scheres, J. ter Maat, M. Giesbers, H. Zuilhof

Research output: Contribution to journalArticleAcademicpeer-review

22 Citations (Scopus)

Abstract

This work describes a new route for patterning organic monolayers on oxide-free silicon by microcontact printing (µCP) on a preformed, reactive, acid-fluoride-terminated monolayer. This indirect printing approach is fast and easily preserves the oxide-free and well-defined monolayer-silicon interface, which is the most important property for potential applications in biosensing and molecular electronics. Water-contact-angle measurements, ellipsometry, attenuated total reflection infrared spectroscopy, and X-ray photoelectron spectroscopy (XPS) demonstrate the formation of the initial acid-fluoride-terminated monolayers without upside-down attachment. Subsequent printing for twenty seconds with an N-hexadecylamine-inked poly(dimethylsiloxane) stamp results in well-defined 5-µm N-hexadecylamide dots, as evidenced by atomic force microscopy and scanning electron microscopy. Printing with a flat stamp allows investigation of the efficiency of amide formation by µCP and water-contact-angle measurements, ellipsometry, and XPS reveal the quantitative conversion of the acid fluoride groups to the corresponding amide within twenty seconds. The absence of silicon oxide, even after immersion in water for 16 h, demonstrates that the oxide-free monolayer-silicon interface is easily preserved by this patterning route. Finally, it is shown by fluorescence microscopy that complex biomolecules, like functionalized oligo-DNA, can also be immobilized on the oxide-free silicon surface via µCP
Original languageEnglish
Pages (from-to)642-650
JournalSmall
Volume6
Issue number5
DOIs
Publication statusPublished - 2010

Fingerprint

Printing
Silicon
Fluorides
Oxides
Monolayers
Acids
Photoelectron Spectroscopy
Ellipsometry
Angle measurement
Amides
Contact angle
Water
X ray photoelectron spectroscopy
Molecular electronics
Atomic Force Microscopy
Fluorescence microscopy
Silicon oxides
Biomolecules
Immersion
Polydimethylsiloxane

Keywords

  • self-assembled monolayers
  • hydrogen-terminated silicon
  • covalently attached monolayers
  • metal-semiconductor diodes
  • linked organic monolayers
  • extremely mild attachment
  • alkyl monolayers
  • porous silicon
  • si(111) surfaces
  • click chemistry

Cite this

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abstract = "This work describes a new route for patterning organic monolayers on oxide-free silicon by microcontact printing (µCP) on a preformed, reactive, acid-fluoride-terminated monolayer. This indirect printing approach is fast and easily preserves the oxide-free and well-defined monolayer-silicon interface, which is the most important property for potential applications in biosensing and molecular electronics. Water-contact-angle measurements, ellipsometry, attenuated total reflection infrared spectroscopy, and X-ray photoelectron spectroscopy (XPS) demonstrate the formation of the initial acid-fluoride-terminated monolayers without upside-down attachment. Subsequent printing for twenty seconds with an N-hexadecylamine-inked poly(dimethylsiloxane) stamp results in well-defined 5-µm N-hexadecylamide dots, as evidenced by atomic force microscopy and scanning electron microscopy. Printing with a flat stamp allows investigation of the efficiency of amide formation by µCP and water-contact-angle measurements, ellipsometry, and XPS reveal the quantitative conversion of the acid fluoride groups to the corresponding amide within twenty seconds. The absence of silicon oxide, even after immersion in water for 16 h, demonstrates that the oxide-free monolayer-silicon interface is easily preserved by this patterning route. Finally, it is shown by fluorescence microscopy that complex biomolecules, like functionalized oligo-DNA, can also be immobilized on the oxide-free silicon surface via µCP",
keywords = "self-assembled monolayers, hydrogen-terminated silicon, covalently attached monolayers, metal-semiconductor diodes, linked organic monolayers, extremely mild attachment, alkyl monolayers, porous silicon, si(111) surfaces, click chemistry",
author = "L.M.W. Scheres and {ter Maat}, J. and M. Giesbers and H. Zuilhof",
year = "2010",
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language = "English",
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}

Microcontact Printing onto Oxide-Free Silicon via Highly Reactive Acid Fluoride-Functionalized Monolayers. / Scheres, L.M.W.; ter Maat, J.; Giesbers, M.; Zuilhof, H.

In: Small, Vol. 6, No. 5, 2010, p. 642-650.

Research output: Contribution to journalArticleAcademicpeer-review

TY - JOUR

T1 - Microcontact Printing onto Oxide-Free Silicon via Highly Reactive Acid Fluoride-Functionalized Monolayers

AU - Scheres, L.M.W.

AU - ter Maat, J.

AU - Giesbers, M.

AU - Zuilhof, H.

PY - 2010

Y1 - 2010

N2 - This work describes a new route for patterning organic monolayers on oxide-free silicon by microcontact printing (µCP) on a preformed, reactive, acid-fluoride-terminated monolayer. This indirect printing approach is fast and easily preserves the oxide-free and well-defined monolayer-silicon interface, which is the most important property for potential applications in biosensing and molecular electronics. Water-contact-angle measurements, ellipsometry, attenuated total reflection infrared spectroscopy, and X-ray photoelectron spectroscopy (XPS) demonstrate the formation of the initial acid-fluoride-terminated monolayers without upside-down attachment. Subsequent printing for twenty seconds with an N-hexadecylamine-inked poly(dimethylsiloxane) stamp results in well-defined 5-µm N-hexadecylamide dots, as evidenced by atomic force microscopy and scanning electron microscopy. Printing with a flat stamp allows investigation of the efficiency of amide formation by µCP and water-contact-angle measurements, ellipsometry, and XPS reveal the quantitative conversion of the acid fluoride groups to the corresponding amide within twenty seconds. The absence of silicon oxide, even after immersion in water for 16 h, demonstrates that the oxide-free monolayer-silicon interface is easily preserved by this patterning route. Finally, it is shown by fluorescence microscopy that complex biomolecules, like functionalized oligo-DNA, can also be immobilized on the oxide-free silicon surface via µCP

AB - This work describes a new route for patterning organic monolayers on oxide-free silicon by microcontact printing (µCP) on a preformed, reactive, acid-fluoride-terminated monolayer. This indirect printing approach is fast and easily preserves the oxide-free and well-defined monolayer-silicon interface, which is the most important property for potential applications in biosensing and molecular electronics. Water-contact-angle measurements, ellipsometry, attenuated total reflection infrared spectroscopy, and X-ray photoelectron spectroscopy (XPS) demonstrate the formation of the initial acid-fluoride-terminated monolayers without upside-down attachment. Subsequent printing for twenty seconds with an N-hexadecylamine-inked poly(dimethylsiloxane) stamp results in well-defined 5-µm N-hexadecylamide dots, as evidenced by atomic force microscopy and scanning electron microscopy. Printing with a flat stamp allows investigation of the efficiency of amide formation by µCP and water-contact-angle measurements, ellipsometry, and XPS reveal the quantitative conversion of the acid fluoride groups to the corresponding amide within twenty seconds. The absence of silicon oxide, even after immersion in water for 16 h, demonstrates that the oxide-free monolayer-silicon interface is easily preserved by this patterning route. Finally, it is shown by fluorescence microscopy that complex biomolecules, like functionalized oligo-DNA, can also be immobilized on the oxide-free silicon surface via µCP

KW - self-assembled monolayers

KW - hydrogen-terminated silicon

KW - covalently attached monolayers

KW - metal-semiconductor diodes

KW - linked organic monolayers

KW - extremely mild attachment

KW - alkyl monolayers

KW - porous silicon

KW - si(111) surfaces

KW - click chemistry

U2 - 10.1002/smll.200901650

DO - 10.1002/smll.200901650

M3 - Article

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SP - 642

EP - 650

JO - Small

JF - Small

SN - 1613-6810

IS - 5

ER -