Microbiota conservation and BMI signatures in adult monozygotic twins

S. Tims, C. Derom, D.M.A.E. Jonkers, R. Vlietinck, W.H. Saris, M. Kleerebezem, W.M. de Vos, E.G. Zoetendal

Research output: Contribution to journalArticleAcademicpeer-review

155 Citations (Scopus)

Abstract

The human gastrointestinal (GI) tract microbiota acts like a virtual organ and is suggested to be of great importance in human energy balance and weight control. This study included 40 monozygotic (MZ) twin pairs to investigate the influence of the human genotype on GI microbiota structure as well as microbial signatures for differences in body mass index (BMI). Phylogenetic microarraying based on 16S rRNA genes demonstrated that MZ twins have more similar microbiotas compared with unrelated subjects (P
Original languageEnglish
Pages (from-to)707-717
JournalISME Journal
Volume7
DOIs
Publication statusPublished - 2013

Keywords

  • human gut
  • crohns-disease
  • phylogenetic microarray
  • intestinal microbiota
  • identical-twins
  • sp nov.
  • bacteria
  • obesity
  • host
  • ecology

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