Method of making isoidide

E. Hagberg (Inventor), K. Martin (Inventor), J. Ee (Inventor), J.E.L. le Notre (Inventor), D.S. van Es (Inventor), J. van Haveren (Inventor)

Research output: Patent


Disclosed is a process for the preparation of isoidide from isosorbide. An aqueous solution of isosorbide is subjected to epimerization in the presence of hydrogen under the influence of a catalyst comprising ruthenium on a support, preferably a carbon support. The process of the invention can be conducted using a relatively low hydrogen pressure, and leads to a desired distribution of epimers, favoring isoidide over isomannide and isosorbide.
Original languageEnglish
Patent numberWO2013125950
Priority date20/02/12
Publication statusPublished - 29 Aug 2013


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