Mechanistic and quantitative aspects of liver tumour promotion in mice

Agriculture & Biology

• liver neoplasms 100%
• dieldrin 94%
• neoplasms 46%
• mice 43%
• dosage 36%
• liver 29%
• dose response 23%
• tetraploidy 19%
• gene induction 17%
• xenobiotics 15%
• HCH (pesticide) 13%
• diploidy 12%
• smooth endoplasmic reticulum 12%
• carcinogens 10%
• cells 9%
• isozymes 8%
• neoplastic processes 8%
• octaploidy 8%
• stereoisomers 6%
• phenobarbital 5%
• DDT (pesticide) 5%
• chronic exposure 5%
• hyperplasia 5%
• carcinogenesis 5%
• hypertrophy 5%
• alanine transaminase 5%
• thymidine 4%
• laboratory animals 4%
• enzymes 4%
• hepatocytes 4%
• cell growth 4%
• receptors 3%
• diet 2%