MCRA Core

J.W. Kruisselbrink; J. Engel; T. van Voorthuijsen; W.J. de Boer; M.S. van Lenthe; H. van der Voet; Gerda van Donkersgoed; Guangchao Chen; Esther De Jong; Jacob van Klaveren

doi:10.5281/zenodo.8074841

MCRA Core

J.W. Kruisselbrink, J. Engel, T. van Voorthuijsen, W.J. de Boer, M.S. van Lenthe, H. van der Voet, Gerda van Donkersgoed, Guangchao Chen, Esther De Jong, Jacob van Klaveren

Biometris

Research output: Non-textual form › Software

Abstract

The Monte Carlo Risk Assessment (MCRA) software contains models for human health risk assessment for combined exposure to multiple chemicals via food intake, inhalation and dermal contact. Models are available to address all major areas of risk assessment, including hazard identification, hazard characterisation, (dietary and non-dietary) exposure assessment and risk assessment. The software supports risk assessments for any group of substances, health effect and population. MCRA also contains models following the guidelines and regulatory methodologies of the European Commission and the European Food Safety Authority (EFSA). The MCRA Core library contains the model implementations of the MCRA software that are used in the MCRA Web platform.

Original language	English
Publisher	Wageningen University & Research
Media of output	Online
DOIs	https://doi.org/10.5281/zenodo.8074841
Publication status	Published - 21 Dec 2023

Keywords

Probabilistic models
Chronic
Risk assessment models
Cumulative risk assessment
Acute
Hazard characterisation
Non-dietary exposure
Dietary exposure

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

Access to Document

10.5281/zenodo.8074841Licence: GNU LGPL

2 Article

Feasibility study Open MCRA
Kruisselbrink, J. W., van Lenthe, M. S., van der Voet, H., de Boer, W. J. & van Klaveren, J. D., 1 Apr 2021, In: EFSA Supporting Publications. 18, 4
Research output: Contribution to journal › Article › Academic › peer-review

Open Access
The MCRA toolbox of models and data to support chemical mixture risk assessment
van der Voet, H., Kruisselbrink, J. W., de Boer, W. J., van Lenthe, M. S., van den Heuvel, J. J. B., Crépet, A., Kennedy, M. C., Zilliacus, J., Beronius, A., Tebby, C., Brochot, C., Luckert, C., Lampen, A., Rorije, E., Sprong, C. & van Klaveren, J. D., Apr 2020, In: Food and Chemical Toxicology. 138, 111185.
Research output: Contribution to journal › Article › Academic › peer-review

Open Access
27 Citations (Scopus)

Cite this

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title = "MCRA Core",

abstract = "The Monte Carlo Risk Assessment (MCRA) software contains models for human health risk assessment for combined exposure to multiple chemicals via food intake, inhalation and dermal contact. Models are available to address all major areas of risk assessment, including hazard identification, hazard characterisation, (dietary and non-dietary) exposure assessment and risk assessment. The software supports risk assessments for any group of substances, health effect and population. MCRA also contains models following the guidelines and regulatory methodologies of the European Commission and the European Food Safety Authority (EFSA). The MCRA Core library contains the model implementations of the MCRA software that are used in the MCRA Web platform.",

keywords = "Probabilistic models, Chronic, Risk assessment models, Cumulative risk assessment, Acute, Hazard characterisation, Non-dietary exposure, Dietary exposure",

author = "J.W. Kruisselbrink and J. Engel and {van Voorthuijsen}, T. and {de Boer}, W.J. and {van Lenthe}, M.S. and {van der Voet}, H. and {van Donkersgoed}, Gerda and Guangchao Chen and {De Jong}, Esther and {van Klaveren}, Jacob",

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language = "English",

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AU - Kruisselbrink, J.W.

AU - Engel, J.

AU - van Voorthuijsen, T.

AU - de Boer, W.J.

AU - van Lenthe, M.S.

AU - van der Voet, H.

AU - van Donkersgoed, Gerda

AU - Chen, Guangchao

AU - De Jong, Esther

AU - van Klaveren, Jacob

PY - 2023/12/21

Y1 - 2023/12/21

N2 - The Monte Carlo Risk Assessment (MCRA) software contains models for human health risk assessment for combined exposure to multiple chemicals via food intake, inhalation and dermal contact. Models are available to address all major areas of risk assessment, including hazard identification, hazard characterisation, (dietary and non-dietary) exposure assessment and risk assessment. The software supports risk assessments for any group of substances, health effect and population. MCRA also contains models following the guidelines and regulatory methodologies of the European Commission and the European Food Safety Authority (EFSA). The MCRA Core library contains the model implementations of the MCRA software that are used in the MCRA Web platform.

AB - The Monte Carlo Risk Assessment (MCRA) software contains models for human health risk assessment for combined exposure to multiple chemicals via food intake, inhalation and dermal contact. Models are available to address all major areas of risk assessment, including hazard identification, hazard characterisation, (dietary and non-dietary) exposure assessment and risk assessment. The software supports risk assessments for any group of substances, health effect and population. MCRA also contains models following the guidelines and regulatory methodologies of the European Commission and the European Food Safety Authority (EFSA). The MCRA Core library contains the model implementations of the MCRA software that are used in the MCRA Web platform.

KW - Probabilistic models

KW - Chronic

KW - Risk assessment models

KW - Cumulative risk assessment

KW - Acute

KW - Hazard characterisation

KW - Non-dietary exposure

KW - Dietary exposure

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DO - 10.5281/zenodo.8074841

M3 - Software

PB - Wageningen University & Research

ER -

MCRA Core

Abstract

Keywords

UN SDGs

Access to Document

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Research output

Feasibility study Open MCRA

The MCRA toolbox of models and data to support chemical mixture risk assessment

Cite this