Mathematical analysis of [13CO2]-expiration curves from human breath tests using [1-13C]-amino acids as oral substrate

V.V.A.M. Schreurs, K. Krawielitzki

Research output: Chapter in Book/Report/Conference proceedingChapterAcademic

Abstract

A [13CO2]-breath test examines the expiration of [13CO2] as function of time after oral intake of a [13C]-labelled test substrate (single dose). In clinical settings, breath test studies are often used as a simple and non-invasive tool to diagnose the activity of metabolic functions. From a nutritional point of view, breath test studies can also be used to trace the catabolic fate of dietary nutrients. The fcMius of this paper was a mathematical analysis of [13CO2]-expiration curves. Human breath test results for [13C]-labelled amino acids (leucine, methionine, lysine) under different dietary conditions were used to illustrate this approach. The mathematical parameters were meant to characterise changes in the catabolic fate of dietary amino acids as influenced by the ingestion of a meal
Original languageEnglish
Title of host publicationProgress in research on energy and protein metabolism
EditorsW.B. Souffrant, C.C. Metges
Place of PublicationRostock-Warnemünde, Germany
Pages239-242
Number of pages840
Publication statusPublished - 2003

Publication series

NameEAAP publication
PublisherWageningen Academic Publishers
Number109

Keywords

  • protein metabolism
  • amino acids
  • isotope labeling
  • carbon
  • breath
  • analysis

Fingerprint

Dive into the research topics of 'Mathematical analysis of [13CO2]-expiration curves from human breath tests using [1-13C]-amino acids as oral substrate'. Together they form a unique fingerprint.

Cite this