Mammalian-type glycosylation in plants by expression of non-mammalian glycosyltransferases

G.J.A. Rouwendal; D.E.A. Florack; H.J. Bosch

Mammalian-type glycosylation in plants by expression of non-mammalian glycosyltransferases

G.J.A. Rouwendal (Inventor), D.E.A. Florack (Inventor), H.J. Bosch (Inventor)

BIOS Applied Metabolic Systems

Research output: Patent

Abstract

The present invention relates to non-mammalian ß-l,4-galactosyltransferases that can be used in their wild-type or in modified forms. The invention further relates to transformed plants and plant cells expressing non-mammalian ß-l,4-galactosyltransferases and methods to produce glycoproteins with altered and preferably mammalian-type glycosylation. The invention additionally provides nucleic acid molecules and expression vectors of non-mammalian ß-l,4-galactosyltransferases.

Original language	English
Patent number	WO2008125972
Priority date	17/04/07
Publication status	Published - 23 Oct 2008

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title = "Mammalian-type glycosylation in plants by expression of non-mammalian glycosyltransferases",

abstract = "The present invention relates to non-mammalian {\ss}-l,4-galactosyltransferases that can be used in their wild-type or in modified forms. The invention further relates to transformed plants and plant cells expressing non-mammalian {\ss}-l,4-galactosyltransferases and methods to produce glycoproteins with altered and preferably mammalian-type glycosylation. The invention additionally provides nucleic acid molecules and expression vectors of non-mammalian {\ss}-l,4-galactosyltransferases.",

author = "G.J.A. Rouwendal and D.E.A. Florack and H.J. Bosch",

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T1 - Mammalian-type glycosylation in plants by expression of non-mammalian glycosyltransferases

AU - Rouwendal, G.J.A.

AU - Florack, D.E.A.

AU - Bosch, H.J.

PY - 2008/10/23

Y1 - 2008/10/23

N2 - The present invention relates to non-mammalian ß-l,4-galactosyltransferases that can be used in their wild-type or in modified forms. The invention further relates to transformed plants and plant cells expressing non-mammalian ß-l,4-galactosyltransferases and methods to produce glycoproteins with altered and preferably mammalian-type glycosylation. The invention additionally provides nucleic acid molecules and expression vectors of non-mammalian ß-l,4-galactosyltransferases.

AB - The present invention relates to non-mammalian ß-l,4-galactosyltransferases that can be used in their wild-type or in modified forms. The invention further relates to transformed plants and plant cells expressing non-mammalian ß-l,4-galactosyltransferases and methods to produce glycoproteins with altered and preferably mammalian-type glycosylation. The invention additionally provides nucleic acid molecules and expression vectors of non-mammalian ß-l,4-galactosyltransferases.

M3 - Patent

M1 - WO2008125972

ER -

Mammalian-type glycosylation in plants by expression of non-mammalian glycosyltransferases

Abstract

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