MalariaSphere : a greenhouse-enclosed simulation of a natural Anopheles gambiae (Diptera: Culicidae) ecosystem in western Kenya

B.G.J. Knols, B.N. Njiru, E.M. Mathenge, W.R. Mukabana, J.C. Beier, G.F. Killeen

Research output: Contribution to journalArticleAcademicpeer-review

Abstract

The development and implementation of innovative vector control strategies for malaria control in Africa requires in-depth ecological studies in contained semi-field environments. This particularly applies to the development and release of genetically-engineered vectors that are refractory to Plasmodium infection. Here we describe a modified greenhouse, designed to simulate a natural Anopheles gambiae Giles ecosystem, and the first successful trials to complete the life-cycle of this mosquito vector therein
Original languageEnglish
JournalMalaria Journal
Volume1
DOIs
Publication statusPublished - 2002

Keywords

  • malaria
  • vector control
  • disease control
  • transgenic animals
  • gene transfer
  • anopheles gambiae
  • plasmodium
  • life cycle
  • simulation

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