Maintenance of a healthy trajectory of the intestinal microbiome during aging: A dietary approach

M. Candela; E. Biagi; P. Brigidi; P.W. O'Toole; W.M. de Vos

doi:10.1016/j.mad.2013.12.004

Maintenance of a healthy trajectory of the intestinal microbiome during aging: A dietary approach

M. Candela
, E. Biagi
, P. Brigidi
, P.W. O'Toole
, W.M. de Vos

Research output: Contribution to journal › Article › Academic › peer-review

80 Citations (Scopus)

Abstract

Sharing an intense transgenomic metabolism with the host, the intestinal microbiota is an essential factor for several aspects of the human physiology. However, several age-related factors, such as changes diet, lifestyle, inflammation and frailty, force the deterioration of this intestinal microbiota-host mutualistic interaction, compromising the possibility to reach longevity. In this scenario, the NU-AGE project involves the development of dietary interventions specifically tailored to the maintenance of a healthy trajectory of the intestinal microbiome, counteracting all processes connected to the pathophysiology of the human aging

Original language	English
Pages (from-to)	70-75
Journal	Mechanisms of Ageing and Development
Volume	136-137
DOIs	https://doi.org/10.1016/j.mad.2013.12.004
Publication status	Published - 2014

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

SDG 3 Good Health and Well-being

Keywords

gut microbiota
fecal microbiota
immune-system
elderly-patients
human longevity
age
disease
immunosenescence
intervention
enterotypes

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10.1016/j.mad.2013.12.004

NU-AGE: New dietary strategies addressing the specific needs of elderly population for an healthy ageing in Europe
1/05/11 → 30/04/16
Project: EU research project

Cite this

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title = "Maintenance of a healthy trajectory of the intestinal microbiome during aging: A dietary approach",

abstract = "Sharing an intense transgenomic metabolism with the host, the intestinal microbiota is an essential factor for several aspects of the human physiology. However, several age-related factors, such as changes diet, lifestyle, inflammation and frailty, force the deterioration of this intestinal microbiota-host mutualistic interaction, compromising the possibility to reach longevity. In this scenario, the NU-AGE project involves the development of dietary interventions specifically tailored to the maintenance of a healthy trajectory of the intestinal microbiome, counteracting all processes connected to the pathophysiology of the human aging",

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author = "M. Candela and E. Biagi and P. Brigidi and P.W. O'Toole and \{de Vos\}, W.M.",

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T1 - Maintenance of a healthy trajectory of the intestinal microbiome during aging: A dietary approach

AU - Candela, M.

AU - Biagi, E.

AU - Brigidi, P.

AU - O'Toole, P.W.

AU - de Vos, W.M.

PY - 2014

Y1 - 2014

N2 - Sharing an intense transgenomic metabolism with the host, the intestinal microbiota is an essential factor for several aspects of the human physiology. However, several age-related factors, such as changes diet, lifestyle, inflammation and frailty, force the deterioration of this intestinal microbiota-host mutualistic interaction, compromising the possibility to reach longevity. In this scenario, the NU-AGE project involves the development of dietary interventions specifically tailored to the maintenance of a healthy trajectory of the intestinal microbiome, counteracting all processes connected to the pathophysiology of the human aging

AB - Sharing an intense transgenomic metabolism with the host, the intestinal microbiota is an essential factor for several aspects of the human physiology. However, several age-related factors, such as changes diet, lifestyle, inflammation and frailty, force the deterioration of this intestinal microbiota-host mutualistic interaction, compromising the possibility to reach longevity. In this scenario, the NU-AGE project involves the development of dietary interventions specifically tailored to the maintenance of a healthy trajectory of the intestinal microbiome, counteracting all processes connected to the pathophysiology of the human aging

KW - gut microbiota

KW - fecal microbiota

KW - immune-system

KW - elderly-patients

KW - human longevity

KW - age

KW - disease

KW - immunosenescence

KW - intervention

KW - enterotypes

U2 - 10.1016/j.mad.2013.12.004

DO - 10.1016/j.mad.2013.12.004

M3 - Article

SN - 0047-6374

VL - 136-137

SP - 70

EP - 75

JO - Mechanisms of Ageing and Development

JF - Mechanisms of Ageing and Development

ER -

Maintenance of a healthy trajectory of the intestinal microbiome during aging: A dietary approach

Abstract

UN SDGs

Keywords

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Projects

NU-AGE: New dietary strategies addressing the specific needs of elderly population for an healthy ageing in Europe

Cite this