Mads floral integrators : Insights into molecular mechanisms of MADS domain proteins in the floral transition

Research output: Thesisinternal PhD, WUAcademic

Abstract

The main aim of this thesis is understanding the molecular regulation of flowering time in Arabidopsis thaliana. More specifically, we focus on of key regulatory genes of flowering that integrate several internal and external flowering signals and examine in detail how they are regulated at the transcriptional and post-transcriptional level. Many of the key regulatory genes encode transcription factors (TFs), which are often functioning in larger protein complexes and are part of complex gene regulatory network. This thesis focuses on two important regulators that are  MADS-domain TFs, SHORT VEGETATIVE PHASE (SVP) and  SUPPERESSOR OF OVEREXPRESSION of CONSTANCE 1 (SOC1) and we studied the protein-protein interactions, chromosomal interactions and TF-DNA interactions, all connections that are part of the gene regulatory networks involved in flowering time control.

Original languageEnglish
QualificationDoctor of Philosophy
Awarding Institution
  • Wageningen University
Supervisors/Advisors
  • Angenent, Gerco, Promotor
  • Immink, Richard, Co-promotor
Award date9 Feb 2018
Place of PublicationWageningen
Publisher
Print ISBNs9789463437356
DOIs
Publication statusPublished - 2018

Fingerprint

flowering
transcription factors
regulator genes
proteins
protein-protein interactions
Arabidopsis thaliana
DNA
gene regulatory networks

Cite this

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title = "Mads floral integrators : Insights into molecular mechanisms of MADS domain proteins in the floral transition",
abstract = "The main aim of this thesis is understanding the molecular regulation of flowering time in Arabidopsis thaliana. More specifically, we focus on of key regulatory genes of flowering that integrate several internal and external flowering signals and examine in detail how they are regulated at the transcriptional and post-transcriptional level. Many of the key regulatory genes encode transcription factors (TFs), which are often functioning in larger protein complexes and are part of complex gene regulatory network. This thesis focuses on two important regulators that are  MADS-domain TFs, SHORT VEGETATIVE PHASE (SVP) and  SUPPERESSOR OF OVEREXPRESSION of CONSTANCE 1 (SOC1) and we studied the protein-protein interactions, chromosomal interactions and TF-DNA interactions, all connections that are part of the gene regulatory networks involved in flowering time control.",
author = "Jamge, {Suraj B.}",
note = "WU thesis 6861 Includes bibliographical references. - With summaries in Dutch and English",
year = "2018",
doi = "10.18174/430710",
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publisher = "Wageningen University",
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Mads floral integrators : Insights into molecular mechanisms of MADS domain proteins in the floral transition. / Jamge, Suraj B.

Wageningen : Wageningen University, 2018. 206 p.

Research output: Thesisinternal PhD, WUAcademic

TY - THES

T1 - Mads floral integrators : Insights into molecular mechanisms of MADS domain proteins in the floral transition

AU - Jamge, Suraj B.

N1 - WU thesis 6861 Includes bibliographical references. - With summaries in Dutch and English

PY - 2018

Y1 - 2018

N2 - The main aim of this thesis is understanding the molecular regulation of flowering time in Arabidopsis thaliana. More specifically, we focus on of key regulatory genes of flowering that integrate several internal and external flowering signals and examine in detail how they are regulated at the transcriptional and post-transcriptional level. Many of the key regulatory genes encode transcription factors (TFs), which are often functioning in larger protein complexes and are part of complex gene regulatory network. This thesis focuses on two important regulators that are  MADS-domain TFs, SHORT VEGETATIVE PHASE (SVP) and  SUPPERESSOR OF OVEREXPRESSION of CONSTANCE 1 (SOC1) and we studied the protein-protein interactions, chromosomal interactions and TF-DNA interactions, all connections that are part of the gene regulatory networks involved in flowering time control.

AB - The main aim of this thesis is understanding the molecular regulation of flowering time in Arabidopsis thaliana. More specifically, we focus on of key regulatory genes of flowering that integrate several internal and external flowering signals and examine in detail how they are regulated at the transcriptional and post-transcriptional level. Many of the key regulatory genes encode transcription factors (TFs), which are often functioning in larger protein complexes and are part of complex gene regulatory network. This thesis focuses on two important regulators that are  MADS-domain TFs, SHORT VEGETATIVE PHASE (SVP) and  SUPPERESSOR OF OVEREXPRESSION of CONSTANCE 1 (SOC1) and we studied the protein-protein interactions, chromosomal interactions and TF-DNA interactions, all connections that are part of the gene regulatory networks involved in flowering time control.

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