Macrophage vesicles in antidiabetic drug action

Rinke Stienstra; Eric Kalkhoven

doi:10.1038/s42255-024-01030-x

Macrophage vesicles in antidiabetic drug action

Rinke Stienstra, Eric Kalkhoven^*

^*Corresponding author for this work

Nutrition, Metabolism and Genomics

Research output: Contribution to journal › Comment/Letter to the editor › Academic

1 Citation (Scopus)

Abstract

Thiazolidinediones (TZDs) are potent insulin-sensitizing drugs, but their use is accompanied by adverse side-effects. Rohm et al. now report that TZD-stimulated macrophages release miR-690-containing vesicles that improve insulin sensitization and bypass unwanted side-effects.

Original language	English
Pages (from-to)	785-786
Journal	Nature Metabolism
Volume	6
Issue number	5
Early online date	11 Apr 2024
DOIs	https://doi.org/10.1038/s42255-024-01030-x
Publication status	Published - 2024

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10.1038/s42255-024-01030-x

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title = "Macrophage vesicles in antidiabetic drug action",

abstract = "Thiazolidinediones (TZDs) are potent insulin-sensitizing drugs, but their use is accompanied by adverse side-effects. Rohm et al. now report that TZD-stimulated macrophages release miR-690-containing vesicles that improve insulin sensitization and bypass unwanted side-effects.",

author = "Rinke Stienstra and Eric Kalkhoven",

year = "2024",

doi = "10.1038/s42255-024-01030-x",

language = "English",

volume = "6",

pages = "785--786",

journal = "Nature Metabolism",

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TY - JOUR

T1 - Macrophage vesicles in antidiabetic drug action

AU - Stienstra, Rinke

AU - Kalkhoven, Eric

PY - 2024

Y1 - 2024

N2 - Thiazolidinediones (TZDs) are potent insulin-sensitizing drugs, but their use is accompanied by adverse side-effects. Rohm et al. now report that TZD-stimulated macrophages release miR-690-containing vesicles that improve insulin sensitization and bypass unwanted side-effects.

AB - Thiazolidinediones (TZDs) are potent insulin-sensitizing drugs, but their use is accompanied by adverse side-effects. Rohm et al. now report that TZD-stimulated macrophages release miR-690-containing vesicles that improve insulin sensitization and bypass unwanted side-effects.

U2 - 10.1038/s42255-024-01030-x

DO - 10.1038/s42255-024-01030-x

M3 - Comment/Letter to the editor

AN - SCOPUS:85190305808

SN - 2522-5812

VL - 6

SP - 785

EP - 786

JO - Nature Metabolism

JF - Nature Metabolism

IS - 5

ER -

Macrophage vesicles in antidiabetic drug action

Abstract

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