Abstract
| Original language | English |
|---|---|
| Pages (from-to) | 484-489 |
| Journal | World Academy of Science, Engineering and Technology |
| Volume | 76 |
| Publication status | Published - 2011 |
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Lipase catalyzed synthesis of aromatic esters of sugar alcohols. / Croitoru, R.; van den Broek, L.A.M.; Frissen, A.E.; Davidescu, C.M.; Peter, F.; Boeriu, C.G.
In: World Academy of Science, Engineering and Technology, Vol. 76, 2011, p. 484-489.Research output: Contribution to journal › Article › Academic › peer-review
TY - JOUR
T1 - Lipase catalyzed synthesis of aromatic esters of sugar alcohols
AU - Croitoru, R.
AU - van den Broek, L.A.M.
AU - Frissen, A.E.
AU - Davidescu, C.M.
AU - Peter, F.
AU - Boeriu, C.G.
PY - 2011
Y1 - 2011
N2 - Commercially available lipases (Candida antarctica lipase B, Novozyme 435, Thermomyces lanuginosus lipase, and Lipozyme TL IM), as well as sol-gel immobilized lipases, have been screened for their ability to acylate regioselectively xylitol, sorbitol, and mannitol with a phenolic ester in a binary mixture of t-butanol and dimethylsulfoxide. HPLC and MALDI-TOF MS analysis revealed the exclusive formation of monoesters for all studied sugar alcohols. The lipases immobilized by the sol-gel entrapment method proved to be efficient catalysts, leading to high conversions (up to 60%) in the investigated acylation reactions. From a sequence of silane precursors with different nonhydrolyzable groups in their structure, the presence of octyl and i-butyl group was most beneficial for the catalytic activity of sol-gel entrapped lipases in the studied process.
AB - Commercially available lipases (Candida antarctica lipase B, Novozyme 435, Thermomyces lanuginosus lipase, and Lipozyme TL IM), as well as sol-gel immobilized lipases, have been screened for their ability to acylate regioselectively xylitol, sorbitol, and mannitol with a phenolic ester in a binary mixture of t-butanol and dimethylsulfoxide. HPLC and MALDI-TOF MS analysis revealed the exclusive formation of monoesters for all studied sugar alcohols. The lipases immobilized by the sol-gel entrapment method proved to be efficient catalysts, leading to high conversions (up to 60%) in the investigated acylation reactions. From a sequence of silane precursors with different nonhydrolyzable groups in their structure, the presence of octyl and i-butyl group was most beneficial for the catalytic activity of sol-gel entrapped lipases in the studied process.
M3 - Article
VL - 76
SP - 484
EP - 489
JO - World Academy of Science, Engineering and Technology
JF - World Academy of Science, Engineering and Technology
SN - 2070-3740
ER -