Abstract
Risk assessment of parsley and dill based teas that contain alkenylbenzenes was performed. To this end the estimated daily intake (EDI) of alkenylbenzenes resulting from use of the teas was quantified. Since most teas appeared to contain more than one alkenylbenzene, a combined risk assessment was performed based on equal potency of all alkenylbenzenes or using a so-called toxic equivalency (TEQ) approach through defining toxic equivalency factors (TEFs) for the different alkenylbenzenes. The EDI values resulting from consuming one cup of tea a day were 0.2-10.1 μg/kg bw for the individual alkenylbenzenes, 0.6-13.1 μg/kg bw for the sum of the alkenylbenzenes, and 0.3-10.7 μg safrole equiv/kg bw for the sum of alkenylbenzenes when expressed in safrole equivalents. The margin of exposure (MOE) values obtained were generally
| Original language | English |
|---|---|
| Pages (from-to) | 8640-8646 |
| Journal | Journal of Agricultural and Food Chemistry |
| Volume | 64 |
| Issue number | 45 |
| DOIs | |
| Publication status | Published - 2016 |
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Keywords
- alkenylbenzenes
- estimated daily intake
- margin of exposure
- parsley and dill based teas
- risk assessment
- toxic equivalency factors
Cite this
}
Level of Alkenylbenzenes in Parsley and Dill Based Teas and Associated Risk Assessment Using the Margin of Exposure Approach. / Alajlouni, Abdul; Al-Malahmeh, Amer J.; Isnaeni, Farida Nur; Wesseling, Sebas; Vervoort, Jacques; Rietjens, Ivonne M.C.M.
In: Journal of Agricultural and Food Chemistry, Vol. 64, No. 45, 2016, p. 8640-8646.Research output: Contribution to journal › Article › Academic › peer-review
TY - JOUR
T1 - Level of Alkenylbenzenes in Parsley and Dill Based Teas and Associated Risk Assessment Using the Margin of Exposure Approach
AU - Alajlouni, Abdul
AU - Al-Malahmeh, Amer J.
AU - Isnaeni, Farida Nur
AU - Wesseling, Sebas
AU - Vervoort, Jacques
AU - Rietjens, Ivonne M.C.M.
PY - 2016
Y1 - 2016
N2 - Risk assessment of parsley and dill based teas that contain alkenylbenzenes was performed. To this end the estimated daily intake (EDI) of alkenylbenzenes resulting from use of the teas was quantified. Since most teas appeared to contain more than one alkenylbenzene, a combined risk assessment was performed based on equal potency of all alkenylbenzenes or using a so-called toxic equivalency (TEQ) approach through defining toxic equivalency factors (TEFs) for the different alkenylbenzenes. The EDI values resulting from consuming one cup of tea a day were 0.2-10.1 μg/kg bw for the individual alkenylbenzenes, 0.6-13.1 μg/kg bw for the sum of the alkenylbenzenes, and 0.3-10.7 μg safrole equiv/kg bw for the sum of alkenylbenzenes when expressed in safrole equivalents. The margin of exposure (MOE) values obtained were generally
AB - Risk assessment of parsley and dill based teas that contain alkenylbenzenes was performed. To this end the estimated daily intake (EDI) of alkenylbenzenes resulting from use of the teas was quantified. Since most teas appeared to contain more than one alkenylbenzene, a combined risk assessment was performed based on equal potency of all alkenylbenzenes or using a so-called toxic equivalency (TEQ) approach through defining toxic equivalency factors (TEFs) for the different alkenylbenzenes. The EDI values resulting from consuming one cup of tea a day were 0.2-10.1 μg/kg bw for the individual alkenylbenzenes, 0.6-13.1 μg/kg bw for the sum of the alkenylbenzenes, and 0.3-10.7 μg safrole equiv/kg bw for the sum of alkenylbenzenes when expressed in safrole equivalents. The margin of exposure (MOE) values obtained were generally
KW - alkenylbenzenes
KW - estimated daily intake
KW - margin of exposure
KW - parsley and dill based teas
KW - risk assessment
KW - toxic equivalency factors
U2 - 10.1021/acs.jafc.6b03650
DO - 10.1021/acs.jafc.6b03650
M3 - Article
VL - 64
SP - 8640
EP - 8646
JO - Journal of Agricultural and Food Chemistry
JF - Journal of Agricultural and Food Chemistry
SN - 0021-8561
IS - 45
ER -