Leisure-time physical activity and risk of type 2 diabetes in patients with established vascular disease or poorly controlled vascular risk factors

B.G. Brouwer, Y. van der Graaf, S.S. Soedamah-Muthu, A.M.J. Wassink, F.L.J. Visseren

Research output: Contribution to journalArticleAcademicpeer-review

8 Citations (Scopus)

Abstract

AIM: To investigate the effect of leisure-time physical activity on the incidence of type 2 diabetes (T2DM) in patients with manifest arterial disease, or poorly controlled risk factors. METHODS: We examined 3940 patients with manifest arterial disease, hypertension or hyperlipidemia, aged 55.2+/-12.2 years. Leisure-time physical activity was measured by a questionnaire and metabolic equivalent (MET) hours per week (h/wk) were calculated. Incident T2DM was evaluated by a specific diabetes questionnaire. RESULTS: Most patients (65%) were physically inactive (0METh/wk), 12% were insufficiently physically active (0-10.5METh/wk) and 23% were sufficiently physically active (>or=10.5METh/wk). During a mean follow-up of 4.7 years, 194 (5%) incident cases of T2DM occurred. Sufficiently physically active patients had a lower incidence of diabetes (hazard ratio (HR) 0.55, 95% confidence interval (CI) 0.37-0.83). Patients who were physically active and not-obese (BMI
Original languageEnglish
Pages (from-to)372-378
JournalDiabetes Research and Clinical Practice
Volume87
Issue number3
DOIs
Publication statusPublished - 2010

Keywords

  • american-heart-association
  • cardiovascular-disease
  • insulin sensitivity
  • glucose-tolerance
  • myocardial-infarction
  • metabolic syndrome
  • arterial-disease
  • exercise
  • mortality
  • men

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