LC-MS-SPE-NMR for the Isolation and Characterization of neo-Clerodane Diterpenoids from Teucrium luteum subsp. flavovirens

A. Castro, S.I.A. Moco, J. Coll, J.J.M. Vervoort

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18 Citations (Scopus)

Abstract

neo-Clerodane diterpenes of plant origin are molecules difficult to monitor due to their nonspecific UV/vis absorption. The present work describes for the first time the application of the LC-MS-SPE-NMR technique for the isolation and characterization of three new neo-clerodane diterpenes, 3ß-hydroxyteucroxylepin and teuluteumin A and teuluteumin B, from Teucrium luteum subsp. flavovirens, harvested from two different locations
Original languageEnglish
Pages (from-to)962-965
JournalJournal of Natural Products
Volume73
Issue number5
DOIs
Publication statusPublished - 2010

Keywords

  • cytotoxic clerodane diterpenoids
  • antifeedant activity
  • structural elucidation
  • biological-activity
  • croton-cajucara
  • rain-forest
  • ajuga
  • stereochemistry
  • scutellaria
  • madagascar

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