Laser welding of pre-functionalized glass substrates: A fabrication and chemical stability study

R.R. Carvalho, S. Reuvekamp, H. Zuilhof, M.T. Blom, E.X. Vrouwe

Research output: Contribution to journalArticleAcademicpeer-review

1 Citation (Scopus)

Abstract

Low-temperature bonding of glass substrates is of great interest in the field of microfluidic-based biosensing, and we study how laser welding could be used for this. This technology allows for the modification of glass channels with temperature-sensitive materials prior to bonding. We study the effects of the welding process by investigation of the thermal degradation of a biotin monolayer and whether it retains the ability to conjugate with fluorescently-labelled streptavidin.
Original languageEnglish
Article number015002
JournalJournal of Micromechanics and Microengineering
Volume28
Issue number1
DOIs
Publication statusPublished - 1 Jan 2018

Keywords

  • glass
  • laser welding
  • low temperature bonding
  • microfluidics

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