Lactate dehydrogenase in the cyanobacterium Microcystis PCC7806

R. Moezelaar; M.J. de Teixeira; L.J. Stal

doi:10.1111/j.1574-6968.1995.tb07448.x

Lactate dehydrogenase in the cyanobacterium Microcystis PCC7806

R. Moezelaar, M.J. de Teixeira, L.J. Stal

Research output: Contribution to journal › Article › Academic › peer-review

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Abstract

The cyanobacterium Microcystis PCC7806 was found to possess an NAD-dependent lactate dehydrogenase (EC 1.1.1.27) which catalyzes the reduction of pyruvate to l-lactate. The enzyme required fructose 1,6-bisphosphate for activity and displayed positive cooperativity towards pyruvate. Lactate was not formed during fermentation by cell suspensions, possibly due to low intracellular concentrations of fructose 1,6-bisphosphate and/or pyruvate.

Original language	English
Pages (from-to)	47-50
Journal	FEMS Microbiology Letters
Volume	127
Issue number	1-2
DOIs	https://doi.org/10.1111/j.1574-6968.1995.tb07448.x
Publication status	Published - 1995

Keywords

Cyanobacteria
Enzyme regulation
Fermentation
Fructose 1,6-bisphosphate
Lactate dehydrogenase
Microcystis PCC7806

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10.1111/j.1574-6968.1995.tb07448.x

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title = "Lactate dehydrogenase in the cyanobacterium Microcystis PCC7806",

abstract = "The cyanobacterium Microcystis PCC7806 was found to possess an NAD-dependent lactate dehydrogenase (EC 1.1.1.27) which catalyzes the reduction of pyruvate to l-lactate. The enzyme required fructose 1,6-bisphosphate for activity and displayed positive cooperativity towards pyruvate. Lactate was not formed during fermentation by cell suspensions, possibly due to low intracellular concentrations of fructose 1,6-bisphosphate and/or pyruvate.",

keywords = "Cyanobacteria, Enzyme regulation, Fermentation, Fructose 1,6-bisphosphate, Lactate dehydrogenase, Microcystis PCC7806",

author = "R. Moezelaar and {de Teixeira}, M.J. and L.J. Stal",

year = "1995",

doi = "10.1111/j.1574-6968.1995.tb07448.x",

language = "English",

volume = "127",

pages = "47--50",

journal = "FEMS Microbiology Letters",

issn = "0378-1097",

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TY - JOUR

T1 - Lactate dehydrogenase in the cyanobacterium Microcystis PCC7806

AU - Moezelaar, R.

AU - de Teixeira, M.J.

AU - Stal, L.J.

PY - 1995

Y1 - 1995

N2 - The cyanobacterium Microcystis PCC7806 was found to possess an NAD-dependent lactate dehydrogenase (EC 1.1.1.27) which catalyzes the reduction of pyruvate to l-lactate. The enzyme required fructose 1,6-bisphosphate for activity and displayed positive cooperativity towards pyruvate. Lactate was not formed during fermentation by cell suspensions, possibly due to low intracellular concentrations of fructose 1,6-bisphosphate and/or pyruvate.

AB - The cyanobacterium Microcystis PCC7806 was found to possess an NAD-dependent lactate dehydrogenase (EC 1.1.1.27) which catalyzes the reduction of pyruvate to l-lactate. The enzyme required fructose 1,6-bisphosphate for activity and displayed positive cooperativity towards pyruvate. Lactate was not formed during fermentation by cell suspensions, possibly due to low intracellular concentrations of fructose 1,6-bisphosphate and/or pyruvate.

KW - Cyanobacteria

KW - Enzyme regulation

KW - Fermentation

KW - Fructose 1,6-bisphosphate

KW - Lactate dehydrogenase

KW - Microcystis PCC7806

U2 - 10.1111/j.1574-6968.1995.tb07448.x

DO - 10.1111/j.1574-6968.1995.tb07448.x

M3 - Article

VL - 127

SP - 47

EP - 50

JO - FEMS Microbiology Letters

JF - FEMS Microbiology Letters

SN - 0378-1097

IS - 1-2

ER -

Lactate dehydrogenase in the cyanobacterium Microcystis PCC7806

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Keywords

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