Isolation and characterization of fusaproliferin, a new toxic metabolite from Fusarium proliferatum

Alberto Ritieni; Vincenzo Fogliano; Giacomino Randazzo; Angela Scarallo; Antonio Logrieco; Antonio Moretti; Luisa Manndina; Antonio Bottalico

doi:10.1002/nt.2620030105

Isolation and characterization of fusaproliferin, a new toxic metabolite from Fusarium proliferatum

Alberto Ritieni, Vincenzo Fogliano, Giacomino Randazzo, Angela Scarallo, Antonio Logrieco^*, Antonio Moretti, Luisa Manndina, Antonio Bottalico

^*Corresponding author for this work

Research output: Contribution to journal › Article › Academic › peer-review

103 Citations (Scopus)

Abstract

A new toxic sesterterpene, named fusaproliferin, was purified from corn kernel cultures (120 ms/kg dry culture) of a strain of Fusarium proliferatum isolated from com ear rot in northern Italy. The strain, designated ITEM‐1494, also produced fumonisin B., (1.500 mg/kg dry culture) and beauvericin (90 mg/kg dry culture), but not moniliformin. To monitor toxicity, the brine shrimp assay was used throughout the isolation procedure. Fusaproliferin had a molecular formula of C₂₇H₄₀O₅, and it is the first sesterterpene isolated from a Fusarium species. © 1995 Wiley‐Liss, Inc.

Original language	English
Pages (from-to)	17-20
Number of pages	4
Journal	Natural Toxins
Volume	3
Issue number	1
DOIs	https://doi.org/10.1002/nt.2620030105
Publication status	Published - 1995
Externally published	Yes

Keywords

Fusaproliferin
Fusarium proliferatum
Mycotoxin
Sesterterpene

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title = "Isolation and characterization of fusaproliferin, a new toxic metabolite from Fusarium proliferatum",

abstract = "A new toxic sesterterpene, named fusaproliferin, was purified from corn kernel cultures (120 ms/kg dry culture) of a strain of Fusarium proliferatum isolated from com ear rot in northern Italy. The strain, designated ITEM‐1494, also produced fumonisin B., (1.500 mg/kg dry culture) and beauvericin (90 mg/kg dry culture), but not moniliformin. To monitor toxicity, the brine shrimp assay was used throughout the isolation procedure. Fusaproliferin had a molecular formula of C27H40O5, and it is the first sesterterpene isolated from a Fusarium species. {\textcopyright} 1995 Wiley‐Liss, Inc.",

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author = "Alberto Ritieni and Vincenzo Fogliano and Giacomino Randazzo and Angela Scarallo and Antonio Logrieco and Antonio Moretti and Luisa Manndina and Antonio Bottalico",

year = "1995",

doi = "10.1002/nt.2620030105",

language = "English",

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journal = "Natural Toxins",

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T1 - Isolation and characterization of fusaproliferin, a new toxic metabolite from Fusarium proliferatum

AU - Ritieni, Alberto

AU - Fogliano, Vincenzo

AU - Randazzo, Giacomino

AU - Scarallo, Angela

AU - Logrieco, Antonio

AU - Moretti, Antonio

AU - Manndina, Luisa

AU - Bottalico, Antonio

PY - 1995

Y1 - 1995

N2 - A new toxic sesterterpene, named fusaproliferin, was purified from corn kernel cultures (120 ms/kg dry culture) of a strain of Fusarium proliferatum isolated from com ear rot in northern Italy. The strain, designated ITEM‐1494, also produced fumonisin B., (1.500 mg/kg dry culture) and beauvericin (90 mg/kg dry culture), but not moniliformin. To monitor toxicity, the brine shrimp assay was used throughout the isolation procedure. Fusaproliferin had a molecular formula of C27H40O5, and it is the first sesterterpene isolated from a Fusarium species. © 1995 Wiley‐Liss, Inc.

AB - A new toxic sesterterpene, named fusaproliferin, was purified from corn kernel cultures (120 ms/kg dry culture) of a strain of Fusarium proliferatum isolated from com ear rot in northern Italy. The strain, designated ITEM‐1494, also produced fumonisin B., (1.500 mg/kg dry culture) and beauvericin (90 mg/kg dry culture), but not moniliformin. To monitor toxicity, the brine shrimp assay was used throughout the isolation procedure. Fusaproliferin had a molecular formula of C27H40O5, and it is the first sesterterpene isolated from a Fusarium species. © 1995 Wiley‐Liss, Inc.

KW - Fusaproliferin

KW - Fusarium proliferatum

KW - Mycotoxin

KW - Sesterterpene

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DO - 10.1002/nt.2620030105

M3 - Article

C2 - 7749578

AN - SCOPUS:0028928733

SN - 1056-9014

VL - 3

SP - 17

EP - 20

JO - Natural Toxins

JF - Natural Toxins

IS - 1

ER -

Isolation and characterization of fusaproliferin, a new toxic metabolite from Fusarium proliferatum

Abstract

Keywords

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