Isolation and characterization of fusaproliferin, a new toxic metabolite from Fusarium proliferatum

Alberto Ritieni, Vincenzo Fogliano, Giacomino Randazzo, Angela Scarallo, Antonio Logrieco*, Antonio Moretti, Luisa Manndina, Antonio Bottalico

*Corresponding author for this work

Research output: Contribution to journalArticleAcademicpeer-review

81 Citations (Scopus)

Abstract

A new toxic sesterterpene, named fusaproliferin, was purified from corn kernel cultures (120 ms/kg dry culture) of a strain of Fusarium proliferatum isolated from com ear rot in northern Italy. The strain, designated ITEM‐1494, also produced fumonisin B., (1.500 mg/kg dry culture) and beauvericin (90 mg/kg dry culture), but not moniliformin. To monitor toxicity, the brine shrimp assay was used throughout the isolation procedure. Fusaproliferin had a molecular formula of C27H40O5, and it is the first sesterterpene isolated from a Fusarium species. © 1995 Wiley‐Liss, Inc.

Original languageEnglish
Pages (from-to)17-20
Number of pages4
JournalNatural Toxins
Volume3
Issue number1
DOIs
Publication statusPublished - 1995
Externally publishedYes

Keywords

  • Fusaproliferin
  • Fusarium proliferatum
  • Mycotoxin
  • Sesterterpene

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