iSO1949_N.oceanica, Genome-scale metabolic model of Nannochloropsis oceanica

S. van Oossanen, N. Ferrer Ledo (Other), V.A.P. Martins dos Santos (Other), M.J. Barbosa (Other), M. Suarez Diez (Other), S. D'Adamo (Other)

Research output: Non-textual formSoftware

Abstract

Genome-scale constraint-based metabolic model (GEM) of the oleaginous microalga Nannochloropsis oceanica. Build through orthology-based reconstruction with AuReMe, using the scaffold GEMs iCre1355 (Chlamyomonas reinhardtii), iLB1027_lipid (Phaeodactylum tricornutum), iRJ1321 (Microchloropsis gaditana) and iNS934 (Microchloropsis salina). Specifically curated on the lipid metabolism of N. oceanica. Contains two 'light acclimation modes', based on continuous steady state cultures acclimated to low light and high light. We used the biomass compositions and oxygen-based photosynthesis-irradiance (PI) curves to set the biomass equation and the non-growth associated maintenance rates. The GEM can predict the effect of light acclimation on CO2-based PI-curves.

Developed by the Bioprocess Engineering (BPE) department and the laboratory of Systems and Synthetic Biology (SSB) of the Wageningen University and Research. Additional information available upon request.
Original languageEnglish
PublisherWageningen University & Research
DOIs
Publication statusPublished - 14 Feb 2024

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