Ionized and Total Magnesium Levels Change during Repeated Exercise in Older Adults

Rieneke Terink, M.G. Balvers, C.C.W.G. Bongers, T.M.H. Eijsvogels, R.F. Witkamp, M. Mensink, M.T. Hopman, J.M.T. Klein Gunnewiek

Research output: Contribution to journalArticleAcademicpeer-review

Abstract

Background: Magnesium is essential for health and performance. Sub-optimal levels have been reported for older persons. In addition, physical exercise is known to temporally decrease magnesium blood concentrations. Objective: To investigate these observations in conjunction we assessed total (tMg) and ionized magnesium (iMg) concentrations in plasma and whole blood, respectively, during 4 consecutive days of exercise in very old vital adults. Design: 68 participants (age 83.7±1.9 years) were monitored on 4 consecutive days at which they walked 30–40km (average ∼8 hours) per day at a self-determined pace. Blood samples were collected one or two days prior to the start of exercise (baseline) and every walking day immediately post-exercise. Samples were analysed for tMg and iMg levels. Results: Baseline tMg and iMg levels were 0.85±0.07 and 0.47±0.07 mmol/L, respectively. iMg decreased after the first walking day (−0.10±0.09 mmol/L, p<.001), increased after the second (+0.11±0.07 mmol/L, p<.001), was unchanged after the third and decreased on the final walking day, all compared to the previous day. tMg was only higher after the third walking day compared to the second walking day (p=.012). In 88% of the participants, iMg levels reached values considered to be sub-optimal at day 1, in 16% of the participants values were sub-optimal for tMg at day 2. Conclusion: Prolonged moderate intensity exercise caused acute effects on iMg levels in a degree comparable to that after a bout of intensive exercise. These effects were not associated with drop-out or health problems. After the second consecutive day of exercise, levels were returned to baseline values, suggesting rapid adaptation/resilience in this population.

Original languageEnglish
Pages (from-to)595-601
Number of pages7
JournalJournal of Nutrition, Health and Aging
Volume23
Issue number6
DOIs
Publication statusPublished - Jun 2019

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Magnesium
Walking
Exercise
Health
Population

Keywords

  • consecutive exercise days
  • micronutrients
  • Older adults
  • reference values

Cite this

Terink, Rieneke ; Balvers, M.G. ; Bongers, C.C.W.G. ; Eijsvogels, T.M.H. ; Witkamp, R.F. ; Mensink, M. ; Hopman, M.T. ; Klein Gunnewiek, J.M.T. / Ionized and Total Magnesium Levels Change during Repeated Exercise in Older Adults. In: Journal of Nutrition, Health and Aging. 2019 ; Vol. 23, No. 6. pp. 595-601.
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title = "Ionized and Total Magnesium Levels Change during Repeated Exercise in Older Adults",
abstract = "Background: Magnesium is essential for health and performance. Sub-optimal levels have been reported for older persons. In addition, physical exercise is known to temporally decrease magnesium blood concentrations. Objective: To investigate these observations in conjunction we assessed total (tMg) and ionized magnesium (iMg) concentrations in plasma and whole blood, respectively, during 4 consecutive days of exercise in very old vital adults. Design: 68 participants (age 83.7±1.9 years) were monitored on 4 consecutive days at which they walked 30–40km (average ∼8 hours) per day at a self-determined pace. Blood samples were collected one or two days prior to the start of exercise (baseline) and every walking day immediately post-exercise. Samples were analysed for tMg and iMg levels. Results: Baseline tMg and iMg levels were 0.85±0.07 and 0.47±0.07 mmol/L, respectively. iMg decreased after the first walking day (−0.10±0.09 mmol/L, p<.001), increased after the second (+0.11±0.07 mmol/L, p<.001), was unchanged after the third and decreased on the final walking day, all compared to the previous day. tMg was only higher after the third walking day compared to the second walking day (p=.012). In 88{\%} of the participants, iMg levels reached values considered to be sub-optimal at day 1, in 16{\%} of the participants values were sub-optimal for tMg at day 2. Conclusion: Prolonged moderate intensity exercise caused acute effects on iMg levels in a degree comparable to that after a bout of intensive exercise. These effects were not associated with drop-out or health problems. After the second consecutive day of exercise, levels were returned to baseline values, suggesting rapid adaptation/resilience in this population.",
keywords = "consecutive exercise days, micronutrients, Older adults, reference values",
author = "Rieneke Terink and M.G. Balvers and C.C.W.G. Bongers and T.M.H. Eijsvogels and R.F. Witkamp and M. Mensink and M.T. Hopman and {Klein Gunnewiek}, J.M.T.",
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Ionized and Total Magnesium Levels Change during Repeated Exercise in Older Adults. / Terink, Rieneke; Balvers, M.G.; Bongers, C.C.W.G.; Eijsvogels, T.M.H.; Witkamp, R.F.; Mensink, M.; Hopman, M.T.; Klein Gunnewiek, J.M.T.

In: Journal of Nutrition, Health and Aging, Vol. 23, No. 6, 06.2019, p. 595-601.

Research output: Contribution to journalArticleAcademicpeer-review

TY - JOUR

T1 - Ionized and Total Magnesium Levels Change during Repeated Exercise in Older Adults

AU - Terink, Rieneke

AU - Balvers, M.G.

AU - Bongers, C.C.W.G.

AU - Eijsvogels, T.M.H.

AU - Witkamp, R.F.

AU - Mensink, M.

AU - Hopman, M.T.

AU - Klein Gunnewiek, J.M.T.

PY - 2019/6

Y1 - 2019/6

N2 - Background: Magnesium is essential for health and performance. Sub-optimal levels have been reported for older persons. In addition, physical exercise is known to temporally decrease magnesium blood concentrations. Objective: To investigate these observations in conjunction we assessed total (tMg) and ionized magnesium (iMg) concentrations in plasma and whole blood, respectively, during 4 consecutive days of exercise in very old vital adults. Design: 68 participants (age 83.7±1.9 years) were monitored on 4 consecutive days at which they walked 30–40km (average ∼8 hours) per day at a self-determined pace. Blood samples were collected one or two days prior to the start of exercise (baseline) and every walking day immediately post-exercise. Samples were analysed for tMg and iMg levels. Results: Baseline tMg and iMg levels were 0.85±0.07 and 0.47±0.07 mmol/L, respectively. iMg decreased after the first walking day (−0.10±0.09 mmol/L, p<.001), increased after the second (+0.11±0.07 mmol/L, p<.001), was unchanged after the third and decreased on the final walking day, all compared to the previous day. tMg was only higher after the third walking day compared to the second walking day (p=.012). In 88% of the participants, iMg levels reached values considered to be sub-optimal at day 1, in 16% of the participants values were sub-optimal for tMg at day 2. Conclusion: Prolonged moderate intensity exercise caused acute effects on iMg levels in a degree comparable to that after a bout of intensive exercise. These effects were not associated with drop-out or health problems. After the second consecutive day of exercise, levels were returned to baseline values, suggesting rapid adaptation/resilience in this population.

AB - Background: Magnesium is essential for health and performance. Sub-optimal levels have been reported for older persons. In addition, physical exercise is known to temporally decrease magnesium blood concentrations. Objective: To investigate these observations in conjunction we assessed total (tMg) and ionized magnesium (iMg) concentrations in plasma and whole blood, respectively, during 4 consecutive days of exercise in very old vital adults. Design: 68 participants (age 83.7±1.9 years) were monitored on 4 consecutive days at which they walked 30–40km (average ∼8 hours) per day at a self-determined pace. Blood samples were collected one or two days prior to the start of exercise (baseline) and every walking day immediately post-exercise. Samples were analysed for tMg and iMg levels. Results: Baseline tMg and iMg levels were 0.85±0.07 and 0.47±0.07 mmol/L, respectively. iMg decreased after the first walking day (−0.10±0.09 mmol/L, p<.001), increased after the second (+0.11±0.07 mmol/L, p<.001), was unchanged after the third and decreased on the final walking day, all compared to the previous day. tMg was only higher after the third walking day compared to the second walking day (p=.012). In 88% of the participants, iMg levels reached values considered to be sub-optimal at day 1, in 16% of the participants values were sub-optimal for tMg at day 2. Conclusion: Prolonged moderate intensity exercise caused acute effects on iMg levels in a degree comparable to that after a bout of intensive exercise. These effects were not associated with drop-out or health problems. After the second consecutive day of exercise, levels were returned to baseline values, suggesting rapid adaptation/resilience in this population.

KW - consecutive exercise days

KW - micronutrients

KW - Older adults

KW - reference values

U2 - 10.1007/s12603-019-1205-y

DO - 10.1007/s12603-019-1205-y

M3 - Article

VL - 23

SP - 595

EP - 601

JO - Journal of Nutrition, Health and Aging

JF - Journal of Nutrition, Health and Aging

SN - 1279-7707

IS - 6

ER -