Iodine supplementation in pregnancy and its effest on child cognition

A. Boonstra, S. Gowachirapant, A.K. Jaiswal, P. Winichagoon, K. Srinivasan, M.B. Zimmerman

Research output: Contribution to journalArticleAcademicpeer-review

28 Citations (Scopus)


Maternal hypothyroidism and hypothyroxenemia due to iodine deficiency have been shown to affect development of the newborn negatively. Maternal iodine supplementation may therefore improve cognitive performance of the offspring, even in areas of mild-to-moderate iodine deficiency (ID). Several iodine supplementation studies have been performed in mildly ID pregnant women in Europe. These studies have shown that iodine supplementation increases maternal urinary iodine (UI) excretion and reduces thyroid volume, as well as prevents increases in infant thyroid volume and thyroglobuline. However, randomized controlled studies with long-term outcomes are lacking. Therefore, two trials were started in 2008 in areas of low iodine status; one in Bangalore, India (n = 325), and another in Bangkok, Thailand (n = 514). Pregnant women were recruited
Original languageEnglish
Pages (from-to)134-136
JournalJournal of Trace Elements in Medicine and Biology
Issue number2-3
Publication statusPublished - 2012


  • deficiency disorders
  • mental performance
  • endemic goiter
  • iodized oil
  • school-age
  • schoolchildren
  • intelligence
  • countries
  • women
  • mothers

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