Invasive pneumococcal disease leads to activation and hyperreactivity of platelets

Rahajeng N. Tunjungputri*, Marien I. de Jonge, Astrid de Greeff, Saskia van Selm, Herma Buys-Bergen, Jose F. Harders-Westerveen, Norbert Stockhofe-Zurwieden, Rolf T. Urbanus, Phillip G. De Groot, Hilde E. Smith, Andre J. van der Ven, Quirijn de Mast

*Corresponding author for this work

Research output: Contribution to journalArticleAcademicpeer-review

9 Citations (Scopus)


Using a novel porcine model of intravenous Streptococcus pneumoniae infection, we showed that invasive pneumococcal infections induce marked platelet activation and hyperreactivity. This may contribute to the vascular complications seen in pneumococcal infection.

Original languageEnglish
Pages (from-to)123-126
JournalThrombosis Research
Publication statusPublished - 2016


  • Infection
  • Myocardial infarction
  • Platelet activation
  • Platelets
  • Pneumonia
  • Streptococcus pneumoniae

Fingerprint Dive into the research topics of 'Invasive pneumococcal disease leads to activation and hyperreactivity of platelets'. Together they form a unique fingerprint.

Cite this