Interaction of silica nanoparticles with phospholipid membranes

H. Pera; J.M. Kleijn; F.A.M. Leermakers

doi:10.1246/cl.2012.1322

Interaction of silica nanoparticles with phospholipid membranes

H. Pera, J.M. Kleijn, F.A.M. Leermakers

WIMEK

Research output: Contribution to journal › Article › Academic › peer-review

9 Citations (Scopus)

Abstract

A fluorescence leakage assay was used in a high-throughput setup to obtain information on the phospholipid vesicle leakage induced by the addition of silica nanoparticles. We showed that this method can be used not only to scan for the conditions under which leakage occurs, but also to obtain quantitative information on the interaction between these nanoparticles and the phospholipid membranes.

Original language	English
Pages (from-to)	1322-1324
Number of pages	2
Journal	Chemistry Letters / Chemical Society of Japan
Volume	41
Issue number	10
DOIs	https://doi.org/10.1246/cl.2012.1322
Publication status	Published - 2012

Keywords

engineered nanoparticles
electroporation

Access to Document

10.1246/cl.2012.1322

ENNSATOX: Engineered Nanoparticle Impact on Aquatic Environments: Structure, Activity and Toxicology
1/07/09 → 30/06/12
Project: EU research project

Cite this

@article{2b146f1780374660bbaf45072a631510,

title = "Interaction of silica nanoparticles with phospholipid membranes",

abstract = "A fluorescence leakage assay was used in a high-throughput setup to obtain information on the phospholipid vesicle leakage induced by the addition of silica nanoparticles. We showed that this method can be used not only to scan for the conditions under which leakage occurs, but also to obtain quantitative information on the interaction between these nanoparticles and the phospholipid membranes.",

keywords = "engineered nanoparticles, electroporation",

author = "H. Pera and J.M. Kleijn and F.A.M. Leermakers",

year = "2012",

doi = "10.1246/cl.2012.1322",

language = "English",

volume = "41",

pages = "1322--1324",

journal = "Chemistry Letters / Chemical Society of Japan",

issn = "0366-7022",

publisher = "Chemical Society of Japan",

number = "10",

}

TY - JOUR

T1 - Interaction of silica nanoparticles with phospholipid membranes

AU - Pera, H.

AU - Kleijn, J.M.

AU - Leermakers, F.A.M.

PY - 2012

Y1 - 2012

N2 - A fluorescence leakage assay was used in a high-throughput setup to obtain information on the phospholipid vesicle leakage induced by the addition of silica nanoparticles. We showed that this method can be used not only to scan for the conditions under which leakage occurs, but also to obtain quantitative information on the interaction between these nanoparticles and the phospholipid membranes.

AB - A fluorescence leakage assay was used in a high-throughput setup to obtain information on the phospholipid vesicle leakage induced by the addition of silica nanoparticles. We showed that this method can be used not only to scan for the conditions under which leakage occurs, but also to obtain quantitative information on the interaction between these nanoparticles and the phospholipid membranes.

KW - engineered nanoparticles

KW - electroporation

U2 - 10.1246/cl.2012.1322

DO - 10.1246/cl.2012.1322

M3 - Article

SN - 0366-7022

VL - 41

SP - 1322

EP - 1324

JO - Chemistry Letters / Chemical Society of Japan

JF - Chemistry Letters / Chemical Society of Japan

IS - 10

ER -

Interaction of silica nanoparticles with phospholipid membranes

Abstract

Keywords

Access to Document

Fingerprint

Projects

ENNSATOX: Engineered Nanoparticle Impact on Aquatic Environments: Structure, Activity and Toxicology

Cite this