Intensification of extraction process through IVDV pretreatment from Eryngium creticum leaves and stems: Maximizing yields and assessing biological activities

Mariam Hammoud, Espérance Debs, Ben van den Broek*, Hiba N. Rajha, Carl Safi, Gijs van Erven, Richard G. Maroun, Ali Chokr, Hassan Rammal, Nicolas Louka

*Corresponding author for this work

Research output: Contribution to journalArticleAcademicpeer-review

Abstract

“Intensification of Vaporization by Decompression to the Vacuum” (IVDV) has initially emerged as a technology primarily employed for expanding and enhancing the texture of biological products. However, its recent applications have showcased significant promise in the realm of extracting bioactive molecules from various plant materials. In this context, optimization using response surface methodology was conducted to investigate the impact of IVDV pretreatment on the extractability of phenolic compounds from Eryngium creticum leaves and stems, as well as their biological activities. Using IVDV preceding the extraction led to higher total phenolic content (TPC) and enhanced antiradical activities in treated materials compared to untreated ones. The optimal processing conditions in terms of water content, steam pressure and treatment time were determined in order to maximize TPC (89.07 and 20.06 mg GAE/g DM in leaves and stems, respectively) and antiradical (DPPH) inhibition percentage (93.51% and 27.54% in leaves and stems, respectively). IVDV-treated extracts showed superior antioxidant, antibacterial and antibiofilm capacities compared to raw extracts. Using RP-UHPLC-PDA-MS, caffeic acid and rosmarinic acid were identified in IVDV-treated leaves. IVDV can be implemented as an innovative treatment applied prior to extraction to boost the recovery of biomolecules from plant matrices.

Original languageEnglish
Article numbere27431
JournalHeliyon
Volume10
Issue number6
DOIs
Publication statusPublished - 30 Mar 2024

Keywords

  • Antibacterial and antibiofilm activities
  • E. creticum
  • IVDV
  • Optimization
  • Phenolic compounds
  • Response surface methodology
  • Stereomicroscopy

Fingerprint

Dive into the research topics of 'Intensification of extraction process through IVDV pretreatment from Eryngium creticum leaves and stems: Maximizing yields and assessing biological activities'. Together they form a unique fingerprint.

Cite this