Integration of growth and patterning during vascular tissue formation in Arabidopsis

B. De Rybel, M. Adibi, A.S. Breda, J.R. Wendrich, M.E. Smit, O. Novák, N. Yamaguchi, S. Yoshida, G. van Isterdael, J. Palovaara, B. Nijsse, M.V. Boekschoten, G.J.E.J. Hooiveld, T. Beeckman, D. Wagner, K. Ljung, C. Fleck, D. Weijers

Research output: Contribution to journalArticleAcademicpeer-review

131 Citations (Scopus)

Abstract

Coordination of cell division and pattern formation is central to tissue and organ development, particularly in plants where walls prevent cell migration. Auxin and cytokinin are both critical for division and patterning, but it is unknown how these hormones converge upon tissue development. We identify a genetic network that reinforces an early embryonic bias in auxin distribution to create a local, nonresponding cytokinin source within the root vascular tissue. Experimental and theoretical evidence shows that these cells act as a tissue organizer by positioning the domain of oriented cell divisions. We further demonstrate that the auxin-cytokinin interaction acts as a spatial incoherent feed-forward loop, which is essential to generate distinct hormonal response zones, thus establishing a stable pattern within a growing vascular tissue.
Original languageEnglish
Article number1255215
Number of pages9
JournalScience
Volume345
Issue number6197
DOIs
Publication statusPublished - 2014

Fingerprint

vascular tissues
cytokinins
auxins
Arabidopsis
cell division
cell movement
plant development
hormones
tissues
cells

Keywords

  • dependent auxin gradients
  • solid-phase extraction
  • shoot apical meristem
  • transcription factor
  • root
  • cytokinins
  • purification
  • expression
  • transport
  • genes

Cite this

De Rybel, B., Adibi, M., Breda, A. S., Wendrich, J. R., Smit, M. E., Novák, O., ... Weijers, D. (2014). Integration of growth and patterning during vascular tissue formation in Arabidopsis. Science, 345(6197), [1255215]. https://doi.org/10.1126/science.1255215
De Rybel, B. ; Adibi, M. ; Breda, A.S. ; Wendrich, J.R. ; Smit, M.E. ; Novák, O. ; Yamaguchi, N. ; Yoshida, S. ; van Isterdael, G. ; Palovaara, J. ; Nijsse, B. ; Boekschoten, M.V. ; Hooiveld, G.J.E.J. ; Beeckman, T. ; Wagner, D. ; Ljung, K. ; Fleck, C. ; Weijers, D. / Integration of growth and patterning during vascular tissue formation in Arabidopsis. In: Science. 2014 ; Vol. 345, No. 6197.
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title = "Integration of growth and patterning during vascular tissue formation in Arabidopsis",
abstract = "Coordination of cell division and pattern formation is central to tissue and organ development, particularly in plants where walls prevent cell migration. Auxin and cytokinin are both critical for division and patterning, but it is unknown how these hormones converge upon tissue development. We identify a genetic network that reinforces an early embryonic bias in auxin distribution to create a local, nonresponding cytokinin source within the root vascular tissue. Experimental and theoretical evidence shows that these cells act as a tissue organizer by positioning the domain of oriented cell divisions. We further demonstrate that the auxin-cytokinin interaction acts as a spatial incoherent feed-forward loop, which is essential to generate distinct hormonal response zones, thus establishing a stable pattern within a growing vascular tissue.",
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author = "{De Rybel}, B. and M. Adibi and A.S. Breda and J.R. Wendrich and M.E. Smit and O. Nov{\'a}k and N. Yamaguchi and S. Yoshida and {van Isterdael}, G. and J. Palovaara and B. Nijsse and M.V. Boekschoten and G.J.E.J. Hooiveld and T. Beeckman and D. Wagner and K. Ljung and C. Fleck and D. Weijers",
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De Rybel, B, Adibi, M, Breda, AS, Wendrich, JR, Smit, ME, Novák, O, Yamaguchi, N, Yoshida, S, van Isterdael, G, Palovaara, J, Nijsse, B, Boekschoten, MV, Hooiveld, GJEJ, Beeckman, T, Wagner, D, Ljung, K, Fleck, C & Weijers, D 2014, 'Integration of growth and patterning during vascular tissue formation in Arabidopsis' Science, vol. 345, no. 6197, 1255215. https://doi.org/10.1126/science.1255215

Integration of growth and patterning during vascular tissue formation in Arabidopsis. / De Rybel, B.; Adibi, M.; Breda, A.S.; Wendrich, J.R.; Smit, M.E.; Novák, O.; Yamaguchi, N.; Yoshida, S.; van Isterdael, G.; Palovaara, J.; Nijsse, B.; Boekschoten, M.V.; Hooiveld, G.J.E.J.; Beeckman, T.; Wagner, D.; Ljung, K.; Fleck, C.; Weijers, D.

In: Science, Vol. 345, No. 6197, 1255215, 2014.

Research output: Contribution to journalArticleAcademicpeer-review

TY - JOUR

T1 - Integration of growth and patterning during vascular tissue formation in Arabidopsis

AU - De Rybel, B.

AU - Adibi, M.

AU - Breda, A.S.

AU - Wendrich, J.R.

AU - Smit, M.E.

AU - Novák, O.

AU - Yamaguchi, N.

AU - Yoshida, S.

AU - van Isterdael, G.

AU - Palovaara, J.

AU - Nijsse, B.

AU - Boekschoten, M.V.

AU - Hooiveld, G.J.E.J.

AU - Beeckman, T.

AU - Wagner, D.

AU - Ljung, K.

AU - Fleck, C.

AU - Weijers, D.

PY - 2014

Y1 - 2014

N2 - Coordination of cell division and pattern formation is central to tissue and organ development, particularly in plants where walls prevent cell migration. Auxin and cytokinin are both critical for division and patterning, but it is unknown how these hormones converge upon tissue development. We identify a genetic network that reinforces an early embryonic bias in auxin distribution to create a local, nonresponding cytokinin source within the root vascular tissue. Experimental and theoretical evidence shows that these cells act as a tissue organizer by positioning the domain of oriented cell divisions. We further demonstrate that the auxin-cytokinin interaction acts as a spatial incoherent feed-forward loop, which is essential to generate distinct hormonal response zones, thus establishing a stable pattern within a growing vascular tissue.

AB - Coordination of cell division and pattern formation is central to tissue and organ development, particularly in plants where walls prevent cell migration. Auxin and cytokinin are both critical for division and patterning, but it is unknown how these hormones converge upon tissue development. We identify a genetic network that reinforces an early embryonic bias in auxin distribution to create a local, nonresponding cytokinin source within the root vascular tissue. Experimental and theoretical evidence shows that these cells act as a tissue organizer by positioning the domain of oriented cell divisions. We further demonstrate that the auxin-cytokinin interaction acts as a spatial incoherent feed-forward loop, which is essential to generate distinct hormonal response zones, thus establishing a stable pattern within a growing vascular tissue.

KW - dependent auxin gradients

KW - solid-phase extraction

KW - shoot apical meristem

KW - transcription factor

KW - root

KW - cytokinins

KW - purification

KW - expression

KW - transport

KW - genes

U2 - 10.1126/science.1255215

DO - 10.1126/science.1255215

M3 - Article

VL - 345

JO - Science

JF - Science

SN - 0036-8075

IS - 6197

M1 - 1255215

ER -

De Rybel B, Adibi M, Breda AS, Wendrich JR, Smit ME, Novák O et al. Integration of growth and patterning during vascular tissue formation in Arabidopsis. Science. 2014;345(6197). 1255215. https://doi.org/10.1126/science.1255215