Integrated Product Recovery Will Boost Industrial Cyanobacterial Processes

Research output: Contribution to journalArticleAcademicpeer-review

1 Citation (Scopus)

Abstract

Cyanobacteria promise to be an important industrial platform for the production of a variety of biobased products such as fuels, plastics, and isoprenoids. Recent advances in synthetic biology have resulted in various cyanobacterial strain improvements. Nevertheless, these new strains are still hampered by product inhibition, resulting in low volumetric productivities, product concentrations, and yields on light. To circumvent these issues, continuous product recovery will need to be applied, resulting in economically viable industrial processes. Optimal product recovery strategies can be developed by considering biological and separation process constraints as well as photobioreactor design. Integrated product recovery will be indispensable to bring the cyanobacterial cell factory to industrial scale.

Original languageEnglish
Pages (from-to)454-463
JournalTrends in Biotechnology
Volume37
Issue number5
Early online date5 Dec 2018
DOIs
Publication statusPublished - May 2019

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Photobioreactors
Synthetic Biology
Biological Phenomena
Terpenes
Cyanobacteria
Plastics
Light
Recovery
Byproducts
Industrial plants
Productivity
Manufacturing and Industrial Facilities

Keywords

  • cyanobacteria
  • process integration
  • product recovery
  • separation

Cite this

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title = "Integrated Product Recovery Will Boost Industrial Cyanobacterial Processes",
abstract = "Cyanobacteria promise to be an important industrial platform for the production of a variety of biobased products such as fuels, plastics, and isoprenoids. Recent advances in synthetic biology have resulted in various cyanobacterial strain improvements. Nevertheless, these new strains are still hampered by product inhibition, resulting in low volumetric productivities, product concentrations, and yields on light. To circumvent these issues, continuous product recovery will need to be applied, resulting in economically viable industrial processes. Optimal product recovery strategies can be developed by considering biological and separation process constraints as well as photobioreactor design. Integrated product recovery will be indispensable to bring the cyanobacterial cell factory to industrial scale.",
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author = "{van den Berg}, Corjan and Eppink, {Michel H.M.} and Wijffels, {Rene H.}",
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Integrated Product Recovery Will Boost Industrial Cyanobacterial Processes. / van den Berg, Corjan; Eppink, Michel H.M.; Wijffels, Rene H.

In: Trends in Biotechnology, Vol. 37, No. 5, 05.2019, p. 454-463.

Research output: Contribution to journalArticleAcademicpeer-review

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AU - Eppink, Michel H.M.

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AB - Cyanobacteria promise to be an important industrial platform for the production of a variety of biobased products such as fuels, plastics, and isoprenoids. Recent advances in synthetic biology have resulted in various cyanobacterial strain improvements. Nevertheless, these new strains are still hampered by product inhibition, resulting in low volumetric productivities, product concentrations, and yields on light. To circumvent these issues, continuous product recovery will need to be applied, resulting in economically viable industrial processes. Optimal product recovery strategies can be developed by considering biological and separation process constraints as well as photobioreactor design. Integrated product recovery will be indispensable to bring the cyanobacterial cell factory to industrial scale.

KW - cyanobacteria

KW - process integration

KW - product recovery

KW - separation

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DO - 10.1016/j.tibtech.2018.11.006

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JF - Trends in Biotechnology

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