Insights on cisgenic plants with durable disease resistance under the European Green Deal

Kevin Schneider*, Jesus Barreiro-Hurle, Jack Vossen, Henk J. Schouten, Geert Kessel, Erik Andreasson, Nam Phuong Kieu, Jörn Strassemeyer, Jordan Hristov, Emilio Rodriguez-Cerezo

*Corresponding author for this work

Research output: Contribution to journalArticleAcademicpeer-review

1 Citation (Scopus)


Significant shares of harvests are lost to pests and diseases, therefore, minimizing these losses could solve part of the supply constraints to feed the world. Cisgenesis is defined as the insertion of genetic material into a recipient organism from a donor that is sexually compatible. Here, we review (i) conventional plant breeding, (ii) cisgenesis, (iii) current pesticide-based disease management, (iv) potential economic implications of cultivating cisgenic crops with durable disease resistances, and (v) potential environmental implications of cultivating such crops; focusing mostly on potatoes, but also apples, with resistances to Phytophthora infestans and Venturia inaequalis, respectively. Adopting cisgenic varieties could provide benefits to farmers and to the environment through lower pesticide use, thus contributing to the European Green Deal target.

Original languageEnglish
Pages (from-to)1027-1040
Number of pages14
JournalTrends in Biotechnology
Issue number8
Publication statusPublished - Aug 2023


  • cisgenesis
  • integrated pest management
  • new genome technique
  • pesticides
  • Phytophthora infestans
  • Venturia inaequalis


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