Abstract
This study shows the effectiveness of vaccination with an E2 subunit vaccine against classical swine fever (CSF) in 2-week-old piglets. Half of the piglets were carrying maternally derived antibodies (MDAs) at the time of vaccination. Three and 6 months later, antibody levels were compared between the two treatments. Moreover, reduction of virus transmission was investigated at 3 and 6 months by doing transmission experiments. The vaccine was found to be capable of reducing virus transmission significantly at both time intervals. Maternal immunity reduced vaccination-induced antibody levels after 3 and 6 months and possibly led to a less effective protection against virus transmission after 6 months.
| Original language | English |
|---|---|
| Pages (from-to) | 3005-3013 |
| Journal | Vaccine |
| Volume | 20 |
| Issue number | 23-24 |
| DOIs | |
| Publication status | Published - 2002 |
UN SDGs
This output contributes to the following UN Sustainable Development Goals (SDGs)
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SDG 3 Good Health and Well-being
Keywords
- marker vaccine
- pseudorabies virus
- 1997-1998 epidemic
- pregnant sows
- e2
- netherlands
- immunity
- protection
- strategies
- disease
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