Inflammation of the adipose tissue: Metabolic consequences during weight (re)gain and loss

Mandala Ajie; Rinke Stienstra

doi:10.1016/B978-0-12-822186-0.00022-5

Inflammation of the adipose tissue: Metabolic consequences during weight (re)gain and loss

Mandala Ajie, Rinke Stienstra

Nutrition, Metabolism and Genomics

Research output: Chapter in Book/Report/Conference proceeding › Chapter › Academic › peer-review

Abstract

Obesity is a known risk factor for the development of various metabolic complications. Losing weight is an effective strategy to reverse many of those complications. However, many individuals regain their lost weight after initial weight loss. Weight regain, even a partial one, reverts many of the metabolic benefits of weight loss. In this chapter, we will focus on the inflammatory responses of the adipose tissue during the development of obesity, weight loss, and regain and will explore the subsequent metabolic consequences. We will describe recent evidence from literature with particular emphasis on the role of adipocytes and macrophages driving the inflammatory response of adipose tissue.

Original language	English
Title of host publication	Visceral and Ectopic Fat
Subtitle of host publication	Risk Factors for Type 2 Diabetes, Atherosclerosis, and Cardiovascular Disease
Editors	Hildo J. Lamb
Publisher	Elsevier
Chapter	14
Pages	205-214
Number of pages	10
ISBN (Electronic)	9780128221860
ISBN (Print)	9780128230121
DOIs	https://doi.org/10.1016/B978-0-12-822186-0.00022-5
Publication status	Published - 20 Jan 2022

Keywords

Adipose tissue
Inflammation
Metabolic complications
Obesity
Weight cycling

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

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10.1016/B978-0-12-822186-0.00022-5

Cite this

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abstract = "Obesity is a known risk factor for the development of various metabolic complications. Losing weight is an effective strategy to reverse many of those complications. However, many individuals regain their lost weight after initial weight loss. Weight regain, even a partial one, reverts many of the metabolic benefits of weight loss. In this chapter, we will focus on the inflammatory responses of the adipose tissue during the development of obesity, weight loss, and regain and will explore the subsequent metabolic consequences. We will describe recent evidence from literature with particular emphasis on the role of adipocytes and macrophages driving the inflammatory response of adipose tissue.",

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Inflammation of the adipose tissue: Metabolic consequences during weight (re)gain and loss. / Ajie, Mandala; Stienstra, Rinke.
Visceral and Ectopic Fat: Risk Factors for Type 2 Diabetes, Atherosclerosis, and Cardiovascular Disease. ed. / Hildo J. Lamb. Elsevier, 2022. p. 205-214.

Research output: Chapter in Book/Report/Conference proceeding › Chapter › Academic › peer-review

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AU - Stienstra, Rinke

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N2 - Obesity is a known risk factor for the development of various metabolic complications. Losing weight is an effective strategy to reverse many of those complications. However, many individuals regain their lost weight after initial weight loss. Weight regain, even a partial one, reverts many of the metabolic benefits of weight loss. In this chapter, we will focus on the inflammatory responses of the adipose tissue during the development of obesity, weight loss, and regain and will explore the subsequent metabolic consequences. We will describe recent evidence from literature with particular emphasis on the role of adipocytes and macrophages driving the inflammatory response of adipose tissue.

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KW - Adipose tissue

KW - Inflammation

KW - Metabolic complications

KW - Obesity

KW - Weight cycling

U2 - 10.1016/B978-0-12-822186-0.00022-5

DO - 10.1016/B978-0-12-822186-0.00022-5

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PB - Elsevier

ER -

Inflammation of the adipose tissue: Metabolic consequences during weight (re)gain and loss

Abstract

Keywords

UN SDGs

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