In vitro generation of interleukin-10-producing regulatory CD4(+) T cells is induced by immunosuppressive drugs and inhibited by T helper 1 (Th1)- and Th2-inducing cytokines

F.J. Barrat; D.J. Cua; P.A. Boonstra; D.F. Richards; C. Crain; H.F.J. Savelkoul; R. de Waal-Malefyt; R.L. Coffman; C.M. Hawrylowicz; A. O'Garra

doi:10.1084/jem.20011629

In vitro generation of interleukin-10-producing regulatory CD4(+) T cells is induced by immunosuppressive drugs and inhibited by T helper 1 (Th1)- and Th2-inducing cytokines

F.J. Barrat, D.J. Cua, P.A. Boonstra, D.F. Richards, C. Crain, H.F.J. Savelkoul, R. de Waal-Malefyt, R.L. Coffman, C.M. Hawrylowicz, A. O'Garra

Cell Biology and Immunology

Research output: Contribution to journal › Article › Academic › peer-review

1019 Citations (Scopus)

Original language	English
Pages (from-to)	603-616.
Journal	Journal of Experimental Medicine
Volume	195
DOIs	https://doi.org/10.1084/jem.20011629
Publication status	Published - 2002

Keywords

Autoimmunity
Dexamethasone
Experimental autoimmune encephalomyelitis
T regulatory lymphocyte
Vitamin D3

Access to Document

10.1084/jem.20011629

Cite this

Barrat, F. J., Cua, D. J., Boonstra, P. A., Richards, D. F., Crain, C., Savelkoul, H. F. J., de Waal-Malefyt, R., Coffman, R. L., Hawrylowicz, C. M., & O'Garra, A. (2002). In vitro generation of interleukin-10-producing regulatory CD4(+) T cells is induced by immunosuppressive drugs and inhibited by T helper 1 (Th1)- and Th2-inducing cytokines. Journal of Experimental Medicine, 195, 603-616. https://doi.org/10.1084/jem.20011629

@article{82d6c043dc6744ec9260bfddd671a140,

title = "In vitro generation of interleukin-10-producing regulatory CD4(+) T cells is induced by immunosuppressive drugs and inhibited by T helper 1 (Th1)- and Th2-inducing cytokines",

keywords = "Autoimmunity, Dexamethasone, Experimental autoimmune encephalomyelitis, T regulatory lymphocyte, Vitamin D3",

author = "F.J. Barrat and D.J. Cua and P.A. Boonstra and D.F. Richards and C. Crain and H.F.J. Savelkoul and {de Waal-Malefyt}, R. and R.L. Coffman and C.M. Hawrylowicz and A. O'Garra",

year = "2002",

doi = "10.1084/jem.20011629",

language = "English",

volume = "195",

pages = "603--616.",

journal = "Journal of Experimental Medicine",

issn = "0022-1007",

publisher = "Rockefeller University Press",

}

Barrat, FJ, Cua, DJ, Boonstra, PA, Richards, DF, Crain, C, Savelkoul, HFJ, de Waal-Malefyt, R, Coffman, RL, Hawrylowicz, CM & O'Garra, A 2002, 'In vitro generation of interleukin-10-producing regulatory CD4(+) T cells is induced by immunosuppressive drugs and inhibited by T helper 1 (Th1)- and Th2-inducing cytokines', Journal of Experimental Medicine, vol. 195, pp. 603-616. https://doi.org/10.1084/jem.20011629

In vitro generation of interleukin-10-producing regulatory CD4(+) T cells is induced by immunosuppressive drugs and inhibited by T helper 1 (Th1)- and Th2-inducing cytokines. / Barrat, F.J.; Cua, D.J.; Boonstra, P.A. et al.
In: Journal of Experimental Medicine, Vol. 195, 2002, p. 603-616.

Research output: Contribution to journal › Article › Academic › peer-review

TY - JOUR

T1 - In vitro generation of interleukin-10-producing regulatory CD4(+) T cells is induced by immunosuppressive drugs and inhibited by T helper 1 (Th1)- and Th2-inducing cytokines

AU - Barrat, F.J.

AU - Cua, D.J.

AU - Boonstra, P.A.

AU - Richards, D.F.

AU - Crain, C.

AU - Savelkoul, H.F.J.

AU - de Waal-Malefyt, R.

AU - Coffman, R.L.

AU - Hawrylowicz, C.M.

AU - O'Garra, A.

PY - 2002

Y1 - 2002

KW - Autoimmunity

KW - Dexamethasone

KW - Experimental autoimmune encephalomyelitis

KW - T regulatory lymphocyte

KW - Vitamin D3

U2 - 10.1084/jem.20011629

DO - 10.1084/jem.20011629

M3 - Article

SN - 0022-1007

VL - 195

SP - 603-616.

JO - Journal of Experimental Medicine

JF - Journal of Experimental Medicine

ER -