In silico prediction of potential allergenicity of proteins according to the FAO/WHO guidelines with the help of Allermatch

M.W.E.J. Fiers; G.A. Kleter; A.A.C.M. Peijnenburg; H. Nijland; J.P.H. Nap; R.C.H.J. van Ham

In silico prediction of potential allergenicity of proteins according to the FAO/WHO guidelines with the help of Allermatch

M.W.E.J. Fiers, G.A. Kleter, A.A.C.M. Peijnenburg, H. Nijland, J.P.H. Nap, R.C.H.J. van Ham

Research output: Chapter in Book/Report/Conference proceeding › Conference paper › Academic

Abstract

Allermatch™ (http://allermatch.org) is a novel web tool for the efficient and standardized prediction of potential allergenicity of proteins according to the current recommendations of the FAO/WHO Expert Consultation, as outlined in the Codex alimentarius. A query amino-acid sequence is compared against the Allermatch™ Allergen database based on current SwissProt and WHO-IUIS allergen lists. The web tool uses a sliding window to identify stretches of 80 amino acids with more than 35% similarity, or identical small stretches of at least six amino acids. The outcome of the analyses is presented in a concise format. Allermatch™ is likely to contribute to improved, transparent and more consistent analyses of potential allergenicity of genetically modified food prior to market release. In the future, the FAO/WHO guidelines may be improved upon. Different methods that could enhance the predictive value of allergen prediction are discussed.

Original language	English
Title of host publication	Allergy Matters: new approaches to allergy prevention and management
Editors	L.J.W.J. Gilissen, H.J. Wichers, H.F.J. Savelkoul, R.J. Bogers
Place of Publication	Dordrecht
Publisher	Springer
Pages	107-118
ISBN (Print)	9781402038969
Publication status	Published - 2006
Event	The international conference on allergy prevention Wageningen, The Netherlands 4-6 February 2004 - Duration: 4 Feb 2004 → 6 Feb 2004

Conference

Conference	The international conference on allergy prevention Wageningen, The Netherlands 4-6 February 2004
Period	4/02/04 → 6/02/04

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

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https://edepot.wur.nl/23429

Cite this

Fiers, M. W. E. J., Kleter, G. A., Peijnenburg, A. A. C. M., Nijland, H., Nap, J. P. H., & van Ham, R. C. H. J. (2006). In silico prediction of potential allergenicity of proteins according to the FAO/WHO guidelines with the help of Allermatch. In L. J. W. J. Gilissen, H. J. Wichers, H. F. J. Savelkoul, & R. J. Bogers (Eds.), Allergy Matters: new approaches to allergy prevention and management (pp. 107-118). Springer. https://edepot.wur.nl/23429

Fiers, M.W.E.J. ; Kleter, G.A. ; Peijnenburg, A.A.C.M. et al. / In silico prediction of potential allergenicity of proteins according to the FAO/WHO guidelines with the help of Allermatch. Allergy Matters: new approaches to allergy prevention and management. editor / L.J.W.J. Gilissen ; H.J. Wichers ; H.F.J. Savelkoul ; R.J. Bogers. Dordrecht : Springer, 2006. pp. 107-118

@inproceedings{64b58f263d14442e9fc1e238ef87b105,

title = "In silico prediction of potential allergenicity of proteins according to the FAO/WHO guidelines with the help of Allermatch",

abstract = "Allermatch{\texttrademark} (http://allermatch.org) is a novel web tool for the efficient and standardized prediction of potential allergenicity of proteins according to the current recommendations of the FAO/WHO Expert Consultation, as outlined in the Codex alimentarius. A query amino-acid sequence is compared against the Allermatch{\texttrademark} Allergen database based on current SwissProt and WHO-IUIS allergen lists. The web tool uses a sliding window to identify stretches of 80 amino acids with more than 35% similarity, or identical small stretches of at least six amino acids. The outcome of the analyses is presented in a concise format. Allermatch{\texttrademark} is likely to contribute to improved, transparent and more consistent analyses of potential allergenicity of genetically modified food prior to market release. In the future, the FAO/WHO guidelines may be improved upon. Different methods that could enhance the predictive value of allergen prediction are discussed.",

author = "M.W.E.J. Fiers and G.A. Kleter and A.A.C.M. Peijnenburg and H. Nijland and J.P.H. Nap and {van Ham}, R.C.H.J.",

year = "2006",

language = "English",

isbn = "9781402038969",

pages = "107--118",

editor = "L.J.W.J. Gilissen and H.J. Wichers and H.F.J. Savelkoul and R.J. Bogers",

booktitle = "Allergy Matters: new approaches to allergy prevention and management",

publisher = "Springer",

address = "Germany",

note = "The international conference on allergy prevention Wageningen, The Netherlands 4-6 February 2004 ; Conference date: 04-02-2004 Through 06-02-2004",

}

Fiers, MWEJ, Kleter, GA, Peijnenburg, AACM, Nijland, H, Nap, JPH & van Ham, RCHJ 2006, In silico prediction of potential allergenicity of proteins according to the FAO/WHO guidelines with the help of Allermatch. in LJWJ Gilissen, HJ Wichers, HFJ Savelkoul & RJ Bogers (eds), Allergy Matters: new approaches to allergy prevention and management. Springer, Dordrecht, pp. 107-118, The international conference on allergy prevention Wageningen, The Netherlands 4-6 February 2004, 4/02/04. <https://edepot.wur.nl/23429>

In silico prediction of potential allergenicity of proteins according to the FAO/WHO guidelines with the help of Allermatch. / Fiers, M.W.E.J.; Kleter, G.A.; Peijnenburg, A.A.C.M. et al.
Allergy Matters: new approaches to allergy prevention and management. ed. / L.J.W.J. Gilissen; H.J. Wichers; H.F.J. Savelkoul; R.J. Bogers. Dordrecht: Springer, 2006. p. 107-118.

Research output: Chapter in Book/Report/Conference proceeding › Conference paper › Academic

TY - GEN

T1 - In silico prediction of potential allergenicity of proteins according to the FAO/WHO guidelines with the help of Allermatch

AU - Fiers, M.W.E.J.

AU - Kleter, G.A.

AU - Peijnenburg, A.A.C.M.

AU - Nijland, H.

AU - Nap, J.P.H.

AU - van Ham, R.C.H.J.

PY - 2006

Y1 - 2006

N2 - Allermatch™ (http://allermatch.org) is a novel web tool for the efficient and standardized prediction of potential allergenicity of proteins according to the current recommendations of the FAO/WHO Expert Consultation, as outlined in the Codex alimentarius. A query amino-acid sequence is compared against the Allermatch™ Allergen database based on current SwissProt and WHO-IUIS allergen lists. The web tool uses a sliding window to identify stretches of 80 amino acids with more than 35% similarity, or identical small stretches of at least six amino acids. The outcome of the analyses is presented in a concise format. Allermatch™ is likely to contribute to improved, transparent and more consistent analyses of potential allergenicity of genetically modified food prior to market release. In the future, the FAO/WHO guidelines may be improved upon. Different methods that could enhance the predictive value of allergen prediction are discussed.

AB - Allermatch™ (http://allermatch.org) is a novel web tool for the efficient and standardized prediction of potential allergenicity of proteins according to the current recommendations of the FAO/WHO Expert Consultation, as outlined in the Codex alimentarius. A query amino-acid sequence is compared against the Allermatch™ Allergen database based on current SwissProt and WHO-IUIS allergen lists. The web tool uses a sliding window to identify stretches of 80 amino acids with more than 35% similarity, or identical small stretches of at least six amino acids. The outcome of the analyses is presented in a concise format. Allermatch™ is likely to contribute to improved, transparent and more consistent analyses of potential allergenicity of genetically modified food prior to market release. In the future, the FAO/WHO guidelines may be improved upon. Different methods that could enhance the predictive value of allergen prediction are discussed.

M3 - Conference paper

SN - 9781402038969

SP - 107

EP - 118

BT - Allergy Matters: new approaches to allergy prevention and management

A2 - Gilissen, L.J.W.J.

A2 - Wichers, H.J.

A2 - Savelkoul, H.F.J.

A2 - Bogers, R.J.

PB - Springer

CY - Dordrecht

T2 - The international conference on allergy prevention Wageningen, The Netherlands 4-6 February 2004

Y2 - 4 February 2004 through 6 February 2004

ER -

Fiers MWEJ, Kleter GA, Peijnenburg AACM, Nijland H, Nap JPH, van Ham RCHJ. In silico prediction of potential allergenicity of proteins according to the FAO/WHO guidelines with the help of Allermatch. In Gilissen LJWJ, Wichers HJ, Savelkoul HFJ, Bogers RJ, editors, Allergy Matters: new approaches to allergy prevention and management. Dordrecht: Springer. 2006. p. 107-118

In silico prediction of potential allergenicity of proteins according to the FAO/WHO guidelines with the help of Allermatch

Abstract

Conference

UN SDGs

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