In plants, highly expressed genes are least compact

X.Y. Ren, O.F.J. Vorst, M.W.E.J. Fiers, W.J. Stiekema, J.P.H. Nap

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94 Citations (Scopus)

Abstract

In both the monocot rice and the dicot Arabidopsis, highly expressed genes have more and longer introns and a larger primary transcript than genes expressed at a low level: higher expressed genes tend to be less compact than lower expressed genes. In animal genomes, it is the other way round. Although the length differences in plant genes are much smaller than in animals, these findings indicate that plant genes are in this respect different from animal genes. Explanations for the relationship between gene configuration and gene expression in animals might be (or might have been) less important in plants. We speculate that selection, if any, on genome configuration has taken a different turn after the divergence of plants and animals
Original languageEnglish
Pages (from-to)528-532
JournalTrends in Genetics
Volume22
Issue number10
DOIs
Publication statusPublished - 2006

Keywords

  • human housekeeping genes
  • rna secondary structure
  • messenger-rna
  • alcohol-dehydrogenase
  • noncoding dna
  • codon usage
  • selection
  • evolution
  • arabidopsis
  • signature

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    Ren, X. Y., Vorst, O. F. J., Fiers, M. W. E. J., Stiekema, W. J., & Nap, J. P. H. (2006). In plants, highly expressed genes are least compact. Trends in Genetics, 22(10), 528-532. https://doi.org/10.1016/j.tig.2006.08.008