Nowadays a large number of compounds are determined in environmental and food samples. Biological tests are used to screen samples for large groups of compounds having a particular effect, but it is often difficult to identify a specific compound when a positive effect is observed. The identification of an unknown compound is a challenge for analytical chemistry in environmental analysis, food analysis, as well as in clinical and forensic toxicology. This study reports on the development of a procedure for the identification of unknown residues in samples suspected of containing illegal substances and samples showing bioactivity in bioassay - or microbiological screening assays. For testing purposes several samples were selected; a number of so-called "cold cases", historical samples that were suspected of containing illegal growth promoting substances, herbal mixtures and sport supplements.
|Name||Report / RIKILT|
|Publisher||Rikilt, Institute of Food Safety|
- analytical methods
- liquid chromatography
- mass spectrometry