Identification of the Trichome Patterning Core Network Using Data from Weak ttg1 Alleles to Constrain the Model Space

Rachappa Balkunde; Anna Deneer; Hanna Bechtel; Bipei Zhang; Stefanie Herberth; Martina Pesch; Benjamin Jaegle; Christian Fleck; Martin Hülskamp

doi:10.1016/j.celrep.2020.108497

Identification of the Trichome Patterning Core Network Using Data from Weak ttg1 Alleles to Constrain the Model Space

Rachappa Balkunde, Anna Deneer, Hanna Bechtel, Bipei Zhang, Stefanie Herberth, Martina Pesch, Benjamin Jaegle, Christian Fleck^*, Martin Hülskamp

^*Corresponding author for this work

Research output: Contribution to journal › Article › Academic › peer-review

Abstract

Mathematical modeling of developmental processes is challenging because most of the parameters are normally unknown. Balkunde et al. use weak trichome patterning mutants to constrain the data and use global mathematical methods to identify the core parts of the complex gene regulatory network that are essential for patterning.

Original language	English
Article number	108497
Journal	Cell Reports
Volume	33
Issue number	11
DOIs	https://doi.org/10.1016/j.celrep.2020.108497
Publication status	Published - 15 Dec 2020

Keywords

Arabidopsis thaliana
gene regulatory network
mathematical modelling
patterning
trichomes

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title = "Identification of the Trichome Patterning Core Network Using Data from Weak ttg1 Alleles to Constrain the Model Space",

abstract = "Mathematical modeling of developmental processes is challenging because most of the parameters are normally unknown. Balkunde et al. use weak trichome patterning mutants to constrain the data and use global mathematical methods to identify the core parts of the complex gene regulatory network that are essential for patterning.",

keywords = "Arabidopsis thaliana, gene regulatory network, mathematical modelling, patterning, trichomes",

author = "Rachappa Balkunde and Anna Deneer and Hanna Bechtel and Bipei Zhang and Stefanie Herberth and Martina Pesch and Benjamin Jaegle and Christian Fleck and Martin H{\"u}lskamp",

year = "2020",

month = dec,

day = "15",

doi = "10.1016/j.celrep.2020.108497",

language = "English",

volume = "33",

journal = "Cell Reports",

issn = "2211-1247",

publisher = "Elsevier",

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Identification of the Trichome Patterning Core Network Using Data from Weak ttg1 Alleles to Constrain the Model Space. / Balkunde, Rachappa; Deneer, Anna; Bechtel, Hanna; Zhang, Bipei; Herberth, Stefanie; Pesch, Martina; Jaegle, Benjamin; Fleck, Christian; Hülskamp, Martin.

In: Cell Reports, Vol. 33, No. 11, 108497, 15.12.2020.

Research output: Contribution to journal › Article › Academic › peer-review

TY - JOUR

T1 - Identification of the Trichome Patterning Core Network Using Data from Weak ttg1 Alleles to Constrain the Model Space

AU - Balkunde, Rachappa

AU - Deneer, Anna

AU - Bechtel, Hanna

AU - Zhang, Bipei

AU - Herberth, Stefanie

AU - Pesch, Martina

AU - Jaegle, Benjamin

AU - Fleck, Christian

AU - Hülskamp, Martin

PY - 2020/12/15

Y1 - 2020/12/15

N2 - Mathematical modeling of developmental processes is challenging because most of the parameters are normally unknown. Balkunde et al. use weak trichome patterning mutants to constrain the data and use global mathematical methods to identify the core parts of the complex gene regulatory network that are essential for patterning.

AB - Mathematical modeling of developmental processes is challenging because most of the parameters are normally unknown. Balkunde et al. use weak trichome patterning mutants to constrain the data and use global mathematical methods to identify the core parts of the complex gene regulatory network that are essential for patterning.

KW - Arabidopsis thaliana

KW - gene regulatory network

KW - mathematical modelling

KW - patterning

KW - trichomes

U2 - 10.1016/j.celrep.2020.108497

DO - 10.1016/j.celrep.2020.108497

M3 - Article

AN - SCOPUS:85097719792

VL - 33

JO - Cell Reports

JF - Cell Reports

SN - 2211-1247

IS - 11

M1 - 108497

ER -