Identification of host-specific effectors mediating pathogenicity of the vascular wilt pathogen Verticillium dahliae

Jinling Li

Research output: Thesisinternal PhD, WU

Abstract

In order to establish disease, many plant pathogens secrete so-called effector molecules to support host colonization, frequently through the modulation of host physiology. Accordingly, many effector molecules have been shown to be pivotal for microbial pathogenesis. Upon infection of its hosts, vascular wilt fungal pathogen Verticillium dahliae secretes effectors to enable host colonization. The aim of the research described in this thesis is to gain more insight into molecular mechanisms of V. dahliae pathogenesis, with a specific focus on the discovery of novel effectors that contribute to the establishment of V. dahliae infections on diverse host plants. Interestingly, we found that pathogenicity of V. dahliae on various plant hosts depends on relatively few effectors, and for some host species even on a single one. Such knowledge is essential for designing and developing novel and effective Verticillium wilt disease management strategies.

Original languageEnglish
QualificationDoctor of Philosophy
Awarding Institution
  • Wageningen University
Supervisors/Advisors
  • Thomma, B.P.H.J., Promotor
  • Faino, Luigi, Co-promotor, External person
Award date13 Feb 2019
Place of PublicationWageningen
Publisher
Print ISBNs9789463435512
DOIs
Publication statusPublished - 13 Feb 2019

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