ICTV Virus Taxonomy Profile: Hepeviridae 2022

Michael A. Purdy, Jan Felix Drexler, Xiang Jin Meng, Heléne Norder, Hiroaki Okamoto, Wim H.M. Van der Poel, Gábor Reuter, William M. de Souza, Rainer G. Ulrich, Donald B. Smith*

*Corresponding author for this work

Research output: Contribution to journalArticleAcademicpeer-review

138 Citations (Scopus)


The family Hepeviridae includes enterically transmitted small quasi-enveloped or non-enveloped positive-sense single-stranded RNA viruses infecting mammals and birds (subfamily Orthohepevirinae) or fish (Parahepevirinae). Hepatitis E virus (genus Paslahepevirus) is responsible for self-limiting acute hepatitis in humans; the infection may become chronic in immunocompromised individuals and extrahepatic manifestations have been described. Avian hepatitis E virus (genus Avihepevirus) causes hepatitis-splenomegaly syndrome in chickens. This is a summary of the International Committee on Taxonomy of Viruses (ICTV) Report on the family Hepeviridae, which is available at www.ictv.global/report/hepeviridae.

Original languageEnglish
Pages (from-to)1-2
JournalThe Journal of general virology
Issue number9
Publication statusPublished - 28 Sept 2022


  • hepatitis E virus
  • Hepeviridae
  • ICTV report
  • taxonomy


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