ICTV virus taxonomy profile: Hepeviridae

Michael A. Purdy*, Tim J. Harrison, S. Jameel, X.J. Meng, H. Okamoto, W.H.M. Van Der Poel, Donald B. Smith, Elliot J. Lefkowitz, Andrew J. Davison, Stuart G. Siddell, Peter Simmonds, Michael J. Adams, Donald B. Smith, Richard J. Orton, Nick J. Knowles

*Corresponding author for this work

Research output: Contribution to journalArticleAcademicpeer-review

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The family Hepeviridae includes enterically transmitted small non-enveloped positive-sense RNA viruses. It includes the genera Piscihepevirus, whose members infect fish, and Orthohepevirus, whose members infect mammals and birds. Members of the genus Orthohepevirus include hepatitis E virus, which is responsible for self-limiting acute hepatitis in humans and several mammalian species; the infection may become chronic in immunocompromised individuals. Extrahepatic manifestations of Guillain–Barré syndrome, neuralgic amyotrophy, glomerulonephritis and pancreatitis have been described in humans. Avian hepatitis E virus causes hepatitis–splenomegaly syndrome in chickens. This is a summary of the International Committee on Taxonomy of Viruses (ICTV) Report on the taxonomy of the Hepeviridae, which is available at www.ictv.global/report/hepeviridae.
Original languageEnglish
Article number000940
Pages (from-to)2645-2646
JournalJournal of General Virology
Issue number11
Publication statusPublished - 1 Nov 2017


  • Avian hepatitis E virus
  • Hepatitis E virus
  • Hepeviridae
  • ICTV
  • Piscihepevirus
  • Swine hepatitis E virus
  • Taxonomy

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    Purdy, M. A., Harrison, T. J., Jameel, S., Meng, X. J., Okamoto, H., Van Der Poel, W. H. M., Smith, D. B., Lefkowitz, E. J., Davison, A. J., Siddell, S. G., Simmonds, P., Adams, M. J., Smith, D. B., Orton, R. J., & Knowles, N. J. (2017). ICTV virus taxonomy profile: Hepeviridae. Journal of General Virology, 98(11), 2645-2646. [000940]. https://doi.org/10.1099/jgv.0.000940