Hybridization studies to modify the host preference of Anopheles gambiae

H.V. Pates, C.F. Curtis, W. Takken

Research output: Contribution to journalArticleAcademicpeer-review

6 Citations (Scopus)

Abstract

A strategy to decrease the vector competence of Anopheles gambiae sensu stricto (Diptera: Culicidae), the most efficient malaria vector in Africa, may consist of exploiting the genes involved in zoophily. Crossing and backcrossing experiments were performed between An.¿gambiae s.s. and the zoophilic sibling species Anopheles quadriannulatus. Mosquito strains were tested in a dual-choice olfactometer to investigate their responses to cow odour. Totals of 12% of An.¿gambiae s.s. and 59% of An.¿quadriannulatus selected the port with the cow odour. Crosses and backcrosses did not show a significant preference for the cow-baited port. The results indicated that anthropophilic behaviour in An.¿gambiae s.s. is a dominant or partially dominant trait, which, in conjunction with the unstable zoophilic behaviour observed in An.¿quadriannulatus, poses a serious obstacle to plans to decrease vector competence by modifying the anthropophilic trait.
Original languageEnglish
Pages (from-to)68-74
JournalMedical and Veterinary Entomology
Volume28
Issue numberS1
DOIs
Publication statusPublished - 2014

Keywords

  • candidate odorant receptors
  • malaria vector mosquito
  • feeding preferences
  • quadriannulatus
  • behavior
  • arabiensis
  • culicidae
  • diptera
  • transmission
  • responses

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