Hybrid formation between African trypanosomes during cyclical transmission

L. Jenni; S. Marti; J. Schweizer; B. Betschart; R.W.F. Le Page; J.M. Wells; A. Tait; P. Paindavoine; E. Pays; M. Steinert

doi:10.1038/322173a0

Hybrid formation between African trypanosomes during cyclical transmission

L. Jenni^*
, S. Marti
, J. Schweizer
, B. Betschart
, R.W.F. Le Page
, J.M. Wells
, A. Tait
, P. Paindavoine
, E. Pays
, M. Steinert

^*Corresponding author for this work

Research output: Contribution to journal › Article › Academic › peer-review

276 Citations (Scopus)

Abstract

Trypanosomes of the species Trypanosoma brucei reproduce primarily by binary fission, but the frequency of enzyme elec-trophoretic variants in natural populations of T. brucei has provided indirect evidence for the existence of a sexual cycle^1-3. These studies, coupled with studies of restriction fragment length polymorphisms of genes encoding glycolytic enzymes⁴, have also provided evidence for T. brucei being diploid. Here we report direct evidence of gene exchange between two different clones of trypanosomes after mixed infection and full cyclical development in the tsetse fly vector.

Original language	English
Pages (from-to)	173-175
Number of pages	3
Journal	Nature
Volume	322
Issue number	6075
DOIs	https://doi.org/10.1038/322173a0
Publication status	Published - 10 Jul 1986
Externally published	Yes

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title = "Hybrid formation between African trypanosomes during cyclical transmission",

abstract = "Trypanosomes of the species Trypanosoma brucei reproduce primarily by binary fission, but the frequency of enzyme elec-trophoretic variants in natural populations of T. brucei has provided indirect evidence for the existence of a sexual cycle1-3. These studies, coupled with studies of restriction fragment length polymorphisms of genes encoding glycolytic enzymes4, have also provided evidence for T. brucei being diploid. Here we report direct evidence of gene exchange between two different clones of trypanosomes after mixed infection and full cyclical development in the tsetse fly vector.",

author = "L. Jenni and S. Marti and J. Schweizer and B. Betschart and \{Le Page\}, R.W.F. and J.M. Wells and A. Tait and P. Paindavoine and E. Pays and M. Steinert",

year = "1986",

month = jul,

day = "10",

doi = "10.1038/322173a0",

language = "English",

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journal = "Nature",

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TY - JOUR

T1 - Hybrid formation between African trypanosomes during cyclical transmission

AU - Jenni, L.

AU - Marti, S.

AU - Schweizer, J.

AU - Betschart, B.

AU - Le Page, R.W.F.

AU - Wells, J.M.

AU - Tait, A.

AU - Paindavoine, P.

AU - Pays, E.

AU - Steinert, M.

PY - 1986/7/10

Y1 - 1986/7/10

N2 - Trypanosomes of the species Trypanosoma brucei reproduce primarily by binary fission, but the frequency of enzyme elec-trophoretic variants in natural populations of T. brucei has provided indirect evidence for the existence of a sexual cycle1-3. These studies, coupled with studies of restriction fragment length polymorphisms of genes encoding glycolytic enzymes4, have also provided evidence for T. brucei being diploid. Here we report direct evidence of gene exchange between two different clones of trypanosomes after mixed infection and full cyclical development in the tsetse fly vector.

AB - Trypanosomes of the species Trypanosoma brucei reproduce primarily by binary fission, but the frequency of enzyme elec-trophoretic variants in natural populations of T. brucei has provided indirect evidence for the existence of a sexual cycle1-3. These studies, coupled with studies of restriction fragment length polymorphisms of genes encoding glycolytic enzymes4, have also provided evidence for T. brucei being diploid. Here we report direct evidence of gene exchange between two different clones of trypanosomes after mixed infection and full cyclical development in the tsetse fly vector.

U2 - 10.1038/322173a0

DO - 10.1038/322173a0

M3 - Article

C2 - 3724860

AN - SCOPUS:0022490117

SN - 0028-0836

VL - 322

SP - 173

EP - 175

JO - Nature

JF - Nature

IS - 6075

ER -

Hybrid formation between African trypanosomes during cyclical transmission

Abstract

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