How widespread is resistance to invermectin among gastrointestinal nematodes in sheep in The Netherlands? = Hoe wijd verspreid is resistentie tegen ivermectine van maagdarmwormen bij het schaap in Nederland?

F.H.M. Borgsteede, J.C. Verkaik, L. Moll, D. Dercksen, P. Vellema, G. Bavinck

Research output: Contribution to journalArticleAcademicpeer-review

5 Citations (Scopus)

Abstract

In Autumn 2009, a faecal egg count reduction test (FERCT) was carried out on three sheep farms. Groups of 8-11 lambs were treated with ivermectin or moxidectin, with a 14-day interval between treatment and sampling. Ivermectin resistance was present on all three farms. Treatment with ivermectin resulted in a reduction in faecal egg numbers of 94.6%, 63%, and 59%. On two farms, 14 days after treatment pooled faecal samples yielded predominantly larvae of Hamonchus contortus (100% and 98%, respectively). On the third farm, H. contortus and (probably) Teladorsagia circumcincta were resistant to ivermectin (64% and 36% of the larvae, respectively). Treatment with moxidectin resulted in a 100% reduction in egg output in sheep on all three farms. More sensitive culture techniques failed to detect any larvae in samples taken from two farms, but a few Ostertagia-type larvae, probably of T. circumcincta, were detected in samples from the third farm. It can be concluded that gastrointestinal nematodes in sheep from these three farms were resistant to ivermectin, whereas resistance to moxidectin was not detected.
Original languageEnglish
Pages (from-to)782-785
JournalTijdschrift voor Diergeneeskunde
Volume135
Issue number21
Publication statusPublished - 2010

Keywords

  • ivermectin
  • sheep
  • gastrointestinal diseases
  • helminths
  • sheep farming
  • haemonchus contortus
  • anthelmintic resistance
  • teladorsagia-circumcincta
  • haemonchus-contortus
  • moxidectin
  • ostertagia
  • efficacy
  • benzimidazole
  • association
  • strain

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