Horizontal transmission experiment of paratuberculosis

H.J.W. van Roermund, M.C.M. de Jong

Research output: Chapter in Book/Report/Conference proceedingConference paperAcademic

Abstract

In September 2001 two groups of 5 calves were placed between two groups of 6 infectious cows in a row during 3 months (Period 1). Calves were one week old at the start and born in MAP-unsuspected status-10 herds. Cows were artificially (orally) infected at one month of age in Januari 1999. Each calf was housed in an open box (to avoid injuries) between two cows, and their position in the row was randomly changed every two weeks. Calves were not artificially infected by us. During a second period of 3 months, each group of 5 calves was housed together with 5 new calves (one week old at the start) in a separate group-stable (Period 2). Every two weeks in Period 1 and 2 blood and faecal samples were taken of all animals. After this period, the 20 calves were transferred to a farm (only crops, no other animals) and housed in a row with dividing walls to avoid direct or faecal contact (until summer 2005). Every two months blood and faecal samples were taken of all 20 animals. In autumn 2004 the animals were inseminated.Results of test-positive animals will be shown. Horizontal cow-calf transmission seems to be easy (Period 1). At the highest infection pressure (6 shedding cows of which 3 continuously in Period 1) all calves excreted MAP in their faeces during Period 1 (shortly after infection), and also during Period 2 (when the shedding cows were absent). After that, excretion declined. Horizontal calf-calf transmission did take place (Period 2). The transmission rate (reproduction ratio R0) will be quantified at the end of the experiment, because more animals can still become faecal-culture positive, especially shortly before calving (summer 2005)
Original languageEnglish
Title of host publicationProceedings 8th International Colloquium on Paratuberculosis, Copenhagen, Denmark, 14-18 August 2005
Pages672-678
Publication statusPublished - 2005
Event8th International Colloquium on Paratuberculosis, Copenhagen, Denmark -
Duration: 14 Aug 200518 Aug 2005

Conference

Conference8th International Colloquium on Paratuberculosis, Copenhagen, Denmark
Period14/08/0518/08/05

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    van Roermund, H. J. W., & de Jong, M. C. M. (2005). Horizontal transmission experiment of paratuberculosis. In Proceedings 8th International Colloquium on Paratuberculosis, Copenhagen, Denmark, 14-18 August 2005 (pp. 672-678) http://www.paratuberculosis.org/proc8/abst6_o30.htm