Homocysteine and vitamin B12 status relate to bone turnover markers, broadband ultrasound attenuation, and fractures in healthy elderly people

R.A.M. Dhonukshe-Rutten; S.M.F. Pluijm; C.P.G.M. de Groot; P. Lips; J.H. Smit; W.A. van Staveren

doi:10.1359/JBMR.050202

Homocysteine and vitamin B12 status relate to bone turnover markers, broadband ultrasound attenuation, and fractures in healthy elderly people

R.A.M. Dhonukshe-Rutten, S.M.F. Pluijm, C.P.G.M. de Groot, P. Lips, J.H. Smit, W.A. van Staveren

Research output: Contribution to journal › Article › Academic › peer-review

173 Citations (Scopus)

Abstract

Hyperhomocysteinemia may contribute to the development of osteoporosis. The relationship of Hcy and vitamin B12 with bone turnover markers, BUA, and fracture incidence was studied in 1267 subjects of the Longitudinal Aging Study Amsterdam. High Hcy and low vitamin B12 concentrations were significantly associated with low BUA, high markers of bone turnover, and increased fracture risk

Original language	English
Pages (from-to)	921-929
Journal	Journal of Bone and Mineral Research
Volume	20
Issue number	6
DOIs	https://doi.org/10.1359/JBMR.050202
Publication status	Published - 2005

Keywords

hormone replacement therapy
hip fracture
osteoporotic fractures
postmenopausal women
mineral density
cobalamin deficiency
biochemical markers
methylmalonic acid
quantitative ultrasound
plasma homocysteine

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

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10.1359/JBMR.050202

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title = "Homocysteine and vitamin B12 status relate to bone turnover markers, broadband ultrasound attenuation, and fractures in healthy elderly people",

abstract = "Hyperhomocysteinemia may contribute to the development of osteoporosis. The relationship of Hcy and vitamin B12 with bone turnover markers, BUA, and fracture incidence was studied in 1267 subjects of the Longitudinal Aging Study Amsterdam. High Hcy and low vitamin B12 concentrations were significantly associated with low BUA, high markers of bone turnover, and increased fracture risk",

keywords = "hormone replacement therapy, hip fracture, osteoporotic fractures, postmenopausal women, mineral density, cobalamin deficiency, biochemical markers, methylmalonic acid, quantitative ultrasound, plasma homocysteine",

author = "R.A.M. Dhonukshe-Rutten and S.M.F. Pluijm and {de Groot}, C.P.G.M. and P. Lips and J.H. Smit and {van Staveren}, W.A.",

year = "2005",

doi = "10.1359/JBMR.050202",

language = "English",

volume = "20",

pages = "921--929",

journal = "Journal of Bone and Mineral Research",

issn = "0884-0431",

publisher = "American Society for Bone and Mineral Research",

number = "6",

}

Homocysteine and vitamin B12 status relate to bone turnover markers, broadband ultrasound attenuation, and fractures in healthy elderly people. / Dhonukshe-Rutten, R.A.M.; Pluijm, S.M.F.; de Groot, C.P.G.M.; Lips, P.; Smit, J.H.; van Staveren, W.A.

In: Journal of Bone and Mineral Research, Vol. 20, No. 6, 2005, p. 921-929.

Research output: Contribution to journal › Article › Academic › peer-review

TY - JOUR

T1 - Homocysteine and vitamin B12 status relate to bone turnover markers, broadband ultrasound attenuation, and fractures in healthy elderly people

AU - Dhonukshe-Rutten, R.A.M.

AU - Pluijm, S.M.F.

AU - de Groot, C.P.G.M.

AU - Lips, P.

AU - Smit, J.H.

AU - van Staveren, W.A.

PY - 2005

Y1 - 2005

N2 - Hyperhomocysteinemia may contribute to the development of osteoporosis. The relationship of Hcy and vitamin B12 with bone turnover markers, BUA, and fracture incidence was studied in 1267 subjects of the Longitudinal Aging Study Amsterdam. High Hcy and low vitamin B12 concentrations were significantly associated with low BUA, high markers of bone turnover, and increased fracture risk

AB - Hyperhomocysteinemia may contribute to the development of osteoporosis. The relationship of Hcy and vitamin B12 with bone turnover markers, BUA, and fracture incidence was studied in 1267 subjects of the Longitudinal Aging Study Amsterdam. High Hcy and low vitamin B12 concentrations were significantly associated with low BUA, high markers of bone turnover, and increased fracture risk

KW - hormone replacement therapy

KW - hip fracture

KW - osteoporotic fractures

KW - postmenopausal women

KW - mineral density

KW - cobalamin deficiency

KW - biochemical markers

KW - methylmalonic acid

KW - quantitative ultrasound

KW - plasma homocysteine

U2 - 10.1359/JBMR.050202

DO - 10.1359/JBMR.050202

M3 - Article

VL - 20

SP - 921

EP - 929

JO - Journal of Bone and Mineral Research

JF - Journal of Bone and Mineral Research

SN - 0884-0431

IS - 6

ER -

Homocysteine and vitamin B12 status relate to bone turnover markers, broadband ultrasound attenuation, and fractures in healthy elderly people

Abstract

Keywords

UN SDGs

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