Abstract
Hyperhomocysteinemia may contribute to the development of osteoporosis. The relationship of Hcy and vitamin B12 with bone turnover markers, BUA, and fracture incidence was studied in 1267 subjects of the Longitudinal Aging Study Amsterdam. High Hcy and low vitamin B12 concentrations were significantly associated with low BUA, high markers of bone turnover, and increased fracture risk
Original language | English |
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Pages (from-to) | 921-929 |
Journal | Journal of Bone and Mineral Research |
Volume | 20 |
Issue number | 6 |
DOIs | |
Publication status | Published - 2005 |
Keywords
- hormone replacement therapy
- hip fracture
- osteoporotic fractures
- postmenopausal women
- mineral density
- cobalamin deficiency
- biochemical markers
- methylmalonic acid
- quantitative ultrasound
- plasma homocysteine