High-resolution phylogeny providing insights towards the epidemiology, zoonotic aspects and taxonomy of sapoviruses

A.F. Barry, R. Durães-Carvalho*, Edmilson F. Oliveira-Filho, A. Alfieri, W.H.M. Van der Poel

*Corresponding author for this work

Research output: Contribution to journalArticleAcademicpeer-review

1 Citation (Scopus)

Abstract

The evolution, epidemiology and zoonotic aspects of Sapoviruses (SaV) are still not well explored. In this study, we applied high-resolution phylogeny to investigate the epidemiological and zoonotic origins as well as taxonomic classification of animal and human SaV. Bayesian framework analyses showed an increase in porcine SaV (PoSaV) population dynamics and genetic diversity between 1975 and 1982, resulting in a SaV gene flow and generation of new strains among porcine and human populations. Our results also show the contribution of different animal populations involved in SaV epidemiology and highlight zoonotic aspects, as exemplified by the crucial role that swine, dogs, mink and humans play in SaV spread. Additionally, phylogenetic analysis suggests that bats may play key role in SaV epidemiology. According to our hypothesis, these animals may act as reservoirs or intermediate host species, contributing to viral spread in zoonotic and other epidemiological scenarios and facilitating the generation of new SaV genogroups and genotypes through recombination events. Data from large-scale phylogeny partition based on patristic distance, did not show a correlation between transmission clusters on generation of SaV genogroups, nevertheless we present both important findings about SaV taxonomy and important considerations useful for further taxonomical studies.
Original languageEnglish
Pages (from-to)8-13
JournalInfection, Genetics and Evolution
Volume56
DOIs
Publication statusPublished - 2017

Fingerprint

Sapovirus
Zoonoses
Phylogeny
epidemiology
Epidemiology
phylogeny
taxonomy
intermediate host
animal
bat
population genetics
recombination
gene flow
population dynamics
genotype
Swine
phylogenetics
Genotype
swine
Mink

Keywords

  • Epidemiology
  • Phylogeny
  • Sapoviruses
  • Taxonomy
  • Zoonoses

Cite this

Barry, A.F. ; Durães-Carvalho, R. ; Oliveira-Filho, Edmilson F. ; Alfieri, A. ; Van der Poel, W.H.M. / High-resolution phylogeny providing insights towards the epidemiology, zoonotic aspects and taxonomy of sapoviruses. In: Infection, Genetics and Evolution. 2017 ; Vol. 56. pp. 8-13.
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High-resolution phylogeny providing insights towards the epidemiology, zoonotic aspects and taxonomy of sapoviruses. / Barry, A.F.; Durães-Carvalho, R.; Oliveira-Filho, Edmilson F.; Alfieri, A.; Van der Poel, W.H.M.

In: Infection, Genetics and Evolution, Vol. 56, 2017, p. 8-13.

Research output: Contribution to journalArticleAcademicpeer-review

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