Health and health-related quality of life in pig farmers carrying livestock-associated methicillin-resistant Staphylococcus aureus

B.A.G.L. van Cleef, B.H.B. van Benthem, E.J.M. Verkade, M.M.L. van Rijen, M.F.Q. Kluytmans-van den Bergh, H. Graveland, T. Bosch, K.M.H.W. Verstappen, J.A. WAGENAAR, D. Heederik, J.A.J.W. Kluytmans

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Abstract

There is limited knowledge about the effect of livestock-associated methicillin-resistant Staphylococcus aureus (LA-MRSA) carriage on health-related quality of life (QoL). With this study, we explored whether LA-MRSA causes infections or affects health-related QoL in pig farmers. This prospective cohort study surveyed persons working on 49 farrowing pig farms in The Netherlands for 1 year (2010–2011). On six sampling moments, nasal swabs, environmental samples and questionnaires on activities and infections were collected. At the end of the study year, persons were asked about their QoL using the validated SF-36 and EQ-5D questionnaires. Of 120 persons, 44 (37%) were persistent MRSA carriers. MRSA carriage was not associated with infections, use of antimicrobials, healthcare contact and health-related QoL items in univariate or multivariate analysis, most likely due to the ‘healthy worker effect’. Despite high carriage rates, the impact of LA-MRSA carriage in this population of relatively healthy pig farmers on health and health-related QoL appears limited; more research is needed for confirmation.

Original languageEnglish
Article number144
Pages (from-to)1774-1783
JournalEpidemiology and Infection
DOIs
Publication statusPublished - 2016

Fingerprint

Livestock
Methicillin-Resistant Staphylococcus aureus
Swine
Quality of Life
Health
Healthy Worker Effect
Infection
Nose
Netherlands
Cohort Studies
Multivariate Analysis
Farmers
Prospective Studies
Delivery of Health Care
Research
Population
Surveys and Questionnaires

Keywords

  • Infectious disease epidemiology
  • methicillin-resistant S. aureus (MRSA)
  • public health
  • zoonoses

Cite this

van Cleef, B. A. G. L., van Benthem, B. H. B., Verkade, E. J. M., van Rijen, M. M. L., Kluytmans-van den Bergh, M. F. Q., Graveland, H., ... Kluytmans, J. A. J. W. (2016). Health and health-related quality of life in pig farmers carrying livestock-associated methicillin-resistant Staphylococcus aureus. Epidemiology and Infection, 1774-1783. [144]. https://doi.org/10.1017/S0950268815003192
van Cleef, B.A.G.L. ; van Benthem, B.H.B. ; Verkade, E.J.M. ; van Rijen, M.M.L. ; Kluytmans-van den Bergh, M.F.Q. ; Graveland, H. ; Bosch, T. ; Verstappen, K.M.H.W. ; WAGENAAR, J.A. ; Heederik, D. ; Kluytmans, J.A.J.W. / Health and health-related quality of life in pig farmers carrying livestock-associated methicillin-resistant Staphylococcus aureus. In: Epidemiology and Infection. 2016 ; pp. 1774-1783.
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abstract = "There is limited knowledge about the effect of livestock-associated methicillin-resistant Staphylococcus aureus (LA-MRSA) carriage on health-related quality of life (QoL). With this study, we explored whether LA-MRSA causes infections or affects health-related QoL in pig farmers. This prospective cohort study surveyed persons working on 49 farrowing pig farms in The Netherlands for 1 year (2010–2011). On six sampling moments, nasal swabs, environmental samples and questionnaires on activities and infections were collected. At the end of the study year, persons were asked about their QoL using the validated SF-36 and EQ-5D questionnaires. Of 120 persons, 44 (37{\%}) were persistent MRSA carriers. MRSA carriage was not associated with infections, use of antimicrobials, healthcare contact and health-related QoL items in univariate or multivariate analysis, most likely due to the ‘healthy worker effect’. Despite high carriage rates, the impact of LA-MRSA carriage in this population of relatively healthy pig farmers on health and health-related QoL appears limited; more research is needed for confirmation.",
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author = "{van Cleef}, B.A.G.L. and {van Benthem}, B.H.B. and E.J.M. Verkade and {van Rijen}, M.M.L. and {Kluytmans-van den Bergh}, M.F.Q. and H. Graveland and T. Bosch and K.M.H.W. Verstappen and J.A. WAGENAAR and D. Heederik and J.A.J.W. Kluytmans",
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van Cleef, BAGL, van Benthem, BHB, Verkade, EJM, van Rijen, MML, Kluytmans-van den Bergh, MFQ, Graveland, H, Bosch, T, Verstappen, KMHW, WAGENAAR, JA, Heederik, D & Kluytmans, JAJW 2016, 'Health and health-related quality of life in pig farmers carrying livestock-associated methicillin-resistant Staphylococcus aureus', Epidemiology and Infection, pp. 1774-1783. https://doi.org/10.1017/S0950268815003192

Health and health-related quality of life in pig farmers carrying livestock-associated methicillin-resistant Staphylococcus aureus. / van Cleef, B.A.G.L.; van Benthem, B.H.B.; Verkade, E.J.M.; van Rijen, M.M.L.; Kluytmans-van den Bergh, M.F.Q.; Graveland, H.; Bosch, T.; Verstappen, K.M.H.W.; WAGENAAR, J.A.; Heederik, D.; Kluytmans, J.A.J.W.

In: Epidemiology and Infection, 2016, p. 1774-1783.

Research output: Contribution to journalArticleAcademicpeer-review

TY - JOUR

T1 - Health and health-related quality of life in pig farmers carrying livestock-associated methicillin-resistant Staphylococcus aureus

AU - van Cleef, B.A.G.L.

AU - van Benthem, B.H.B.

AU - Verkade, E.J.M.

AU - van Rijen, M.M.L.

AU - Kluytmans-van den Bergh, M.F.Q.

AU - Graveland, H.

AU - Bosch, T.

AU - Verstappen, K.M.H.W.

AU - WAGENAAR, J.A.

AU - Heederik, D.

AU - Kluytmans, J.A.J.W.

PY - 2016

Y1 - 2016

N2 - There is limited knowledge about the effect of livestock-associated methicillin-resistant Staphylococcus aureus (LA-MRSA) carriage on health-related quality of life (QoL). With this study, we explored whether LA-MRSA causes infections or affects health-related QoL in pig farmers. This prospective cohort study surveyed persons working on 49 farrowing pig farms in The Netherlands for 1 year (2010–2011). On six sampling moments, nasal swabs, environmental samples and questionnaires on activities and infections were collected. At the end of the study year, persons were asked about their QoL using the validated SF-36 and EQ-5D questionnaires. Of 120 persons, 44 (37%) were persistent MRSA carriers. MRSA carriage was not associated with infections, use of antimicrobials, healthcare contact and health-related QoL items in univariate or multivariate analysis, most likely due to the ‘healthy worker effect’. Despite high carriage rates, the impact of LA-MRSA carriage in this population of relatively healthy pig farmers on health and health-related QoL appears limited; more research is needed for confirmation.

AB - There is limited knowledge about the effect of livestock-associated methicillin-resistant Staphylococcus aureus (LA-MRSA) carriage on health-related quality of life (QoL). With this study, we explored whether LA-MRSA causes infections or affects health-related QoL in pig farmers. This prospective cohort study surveyed persons working on 49 farrowing pig farms in The Netherlands for 1 year (2010–2011). On six sampling moments, nasal swabs, environmental samples and questionnaires on activities and infections were collected. At the end of the study year, persons were asked about their QoL using the validated SF-36 and EQ-5D questionnaires. Of 120 persons, 44 (37%) were persistent MRSA carriers. MRSA carriage was not associated with infections, use of antimicrobials, healthcare contact and health-related QoL items in univariate or multivariate analysis, most likely due to the ‘healthy worker effect’. Despite high carriage rates, the impact of LA-MRSA carriage in this population of relatively healthy pig farmers on health and health-related QoL appears limited; more research is needed for confirmation.

KW - Infectious disease epidemiology

KW - methicillin-resistant S. aureus (MRSA)

KW - public health

KW - zoonoses

U2 - 10.1017/S0950268815003192

DO - 10.1017/S0950268815003192

M3 - Article

SP - 1774

EP - 1783

JO - Epidemiology and Infection

JF - Epidemiology and Infection

SN - 0950-2688

M1 - 144

ER -

van Cleef BAGL, van Benthem BHB, Verkade EJM, van Rijen MML, Kluytmans-van den Bergh MFQ, Graveland H et al. Health and health-related quality of life in pig farmers carrying livestock-associated methicillin-resistant Staphylococcus aureus. Epidemiology and Infection. 2016;1774-1783. 144. https://doi.org/10.1017/S0950268815003192